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eIF4A Inhibition Allows Translational Regulation of mRNAs Encoding Proteins Involved in Alzheimer's Disease

Alzheimer's disease (AD) is the main cause of dementia in our increasingly aging population. The debilitating cognitive and behavioral symptoms characteristic of AD make it an extremely distressing illness for patients and carers. Although drugs have been developed to treat AD symptoms and to s...

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Detalles Bibliográficos
Autores principales: Bottley, Andrew, Phillips, Nicola M., Webb, Thomas E., Willis, Anne E., Spriggs, Keith A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2946912/
https://www.ncbi.nlm.nih.gov/pubmed/20927385
http://dx.doi.org/10.1371/journal.pone.0013030

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