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Sustained Spindle-Assembly Checkpoint Response Requires De Novo Transcription and Translation of Cyclin B1
BACKGROUND: Microtubule-targeting drugs induce mitotic delay at pro-metaphase by preventing the spindle assembly checkpoint to be satisfied. However, especially after prolonged treatments, cells can escape this arrest in a process called mitotic slippage. The mechanisms underlying the spindle assemb...
Autores principales: | Mena, Ana Lúcia, Lam, Eric W.-F., Chatterjee, Sukalyan |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2946930/ https://www.ncbi.nlm.nih.gov/pubmed/20927403 http://dx.doi.org/10.1371/journal.pone.0013037 |
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