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Activation of the K(ATP) channel by Mg-nucleotide interaction with SUR1

The mechanism of adenosine triphosphate (ATP)-sensitive potassium (K(ATP)) channel activation by Mg-nucleotides was studied using a mutation (G334D) in the Kir6.2 subunit of the channel that renders K(ATP) channels insensitive to nucleotide inhibition and has no apparent effect on their gating. K(AT...

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Detalles Bibliográficos
Autores principales: Proks, Peter, de Wet, Heidi, Ashcroft, Frances M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2947056/
https://www.ncbi.nlm.nih.gov/pubmed/20876358
http://dx.doi.org/10.1085/jgp.201010475