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Activation of the K(ATP) channel by Mg-nucleotide interaction with SUR1
The mechanism of adenosine triphosphate (ATP)-sensitive potassium (K(ATP)) channel activation by Mg-nucleotides was studied using a mutation (G334D) in the Kir6.2 subunit of the channel that renders K(ATP) channels insensitive to nucleotide inhibition and has no apparent effect on their gating. K(AT...
Autores principales: | Proks, Peter, de Wet, Heidi, Ashcroft, Frances M. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2947056/ https://www.ncbi.nlm.nih.gov/pubmed/20876358 http://dx.doi.org/10.1085/jgp.201010475 |
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