IAP inhibitors enhance co-stimulation to promote tumor immunity

The inhibitor of apoptosis proteins (IAPs) have recently been shown to modulate nuclear factor κB (NF-κB) signaling downstream of tumor necrosis factor (TNF) family receptors, positioning them as essential survival factors in several cancer cell lines, as indicated by the cytotoxic activity of sever...

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Detalles Bibliográficos
Autores principales: Dougan, Michael, Dougan, Stephanie, Slisz, Joanna, Firestone, Brant, Vanneman, Matthew, Draganov, Dobrin, Goyal, Girija, Li, Weibo, Neuberg, Donna, Blumberg, Richard, Hacohen, Nir, Porter, Dale, Zawel, Leigh, Dranoff, Glenn
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2947073/
https://www.ncbi.nlm.nih.gov/pubmed/20837698
http://dx.doi.org/10.1084/jem.20101123

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