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The inhibition of monocarboxylate transporter 2 (MCT2) by AR-C155858 is modulated by the associated ancillary protein

In mammalian cells, MCTs (monocarboxylate transporters) require association with an ancillary protein to enable plasma membrane expression of the active transporter. Basigin is the preferred binding partner for MCT1, MCT3 and MCT4, and embigin for MCT2. In rat and rabbit erythrocytes, MCT1 is associ...

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Detalles Bibliográficos
Autores principales:	Ovens, Matthew J., Manoharan, Christine, Wilson, Marieangela C., Murray, Clarey M., Halestrap, Andrew P.
Formato:	Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2947196/ https://www.ncbi.nlm.nih.gov/pubmed/20695846 http://dx.doi.org/10.1042/BJ20100890

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