Protein kinase Cε mediates Stat3Ser727 phosphorylation, Stat3-regulated gene expression and cell invasion in various human cancer cell lines via integration with MAPK cascade (RAF-1, MEK1/2, and ERK1/2)

Protein kinase C epsilon (PKCε), a novel calcium-independent PKC isoform, has been shown to be a transforming oncogene. PKCε-mediated oncogenic activity is linked to its ability to promote cell survival. However, the mechanisms by which PKCε signals cell survival remain elusive. We found that signal...

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Detalles Bibliográficos
Autores principales: Aziz, Moammir H., Hafeez, Bilal B., Sand, Jordan M., Pierce, David B., Aziz, Saba W., Dreckschmidt, Nancy E., Verma, Ajit K.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2947343/
https://www.ncbi.nlm.nih.gov/pubmed/20228845
http://dx.doi.org/10.1038/onc.2010.63

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