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Sequence signatures and mRNA concentration can explain two-thirds of protein abundance variation in a human cell line
Transcription, mRNA decay, translation and protein degradation are essential processes during eukaryotic gene expression, but their relative global contributions to steady-state protein concentrations in multi-cellular eukaryotes are largely unknown. Using measurements of absolute protein and mRNA a...
| Autores principales: | , , , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
European Molecular Biology Organization
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2947365/ https://www.ncbi.nlm.nih.gov/pubmed/20739923 http://dx.doi.org/10.1038/msb.2010.59 |