Cargando…
A genome-wide scan for common alleles affecting risk for autism
Although autism spectrum disorders (ASDs) have a substantial genetic basis, most of the known genetic risk has been traced to rare variants, principally copy number variants (CNVs). To identify common risk variation, the Autism Genome Project (AGP) Consortium genotyped 1558 rigorously defined ASD fa...
| Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2010
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2947401/ https://www.ncbi.nlm.nih.gov/pubmed/20663923 http://dx.doi.org/10.1093/hmg/ddq307 |
| _version_ | 1782187369929113600 |
|---|---|
| author | Anney, Richard Klei, Lambertus Pinto, Dalila Regan, Regina Conroy, Judith Magalhaes, Tiago R. Correia, Catarina Abrahams, Brett S. Sykes, Nuala Pagnamenta, Alistair T. Almeida, Joana Bacchelli, Elena Bailey, Anthony J. Baird, Gillian Battaglia, Agatino Berney, Tom Bolshakova, Nadia Bölte, Sven Bolton, Patrick F. Bourgeron, Thomas Brennan, Sean Brian, Jessica Carson, Andrew R. Casallo, Guillermo Casey, Jillian Chu, Su H. Cochrane, Lynne Corsello, Christina Crawford, Emily L. Crossett, Andrew Dawson, Geraldine de Jonge, Maretha Delorme, Richard Drmic, Irene Duketis, Eftichia Duque, Frederico Estes, Annette Farrar, Penny Fernandez, Bridget A. Folstein, Susan E. Fombonne, Eric Freitag, Christine M. Gilbert, John Gillberg, Christopher Glessner, Joseph T. Goldberg, Jeremy Green, Jonathan Guter, Stephen J. Hakonarson, Hakon Heron, Elizabeth A. Hill, Matthew Holt, Richard Howe, Jennifer L. Hughes, Gillian Hus, Vanessa Igliozzi, Roberta Kim, Cecilia Klauck, Sabine M. Kolevzon, Alexander Korvatska, Olena Kustanovich, Vlad Lajonchere, Clara M. Lamb, Janine A. Laskawiec, Magdalena Leboyer, Marion Le Couteur, Ann Leventhal, Bennett L. Lionel, Anath C. Liu, Xiao-Qing Lord, Catherine Lotspeich, Linda Lund, Sabata C. Maestrini, Elena Mahoney, William Mantoulan, Carine Marshall, Christian R. McConachie, Helen McDougle, Christopher J. McGrath, Jane McMahon, William M. Melhem, Nadine M. Merikangas, Alison Migita, Ohsuke Minshew, Nancy J. Mirza, Ghazala K. Munson, Jeff Nelson, Stanley F. Noakes, Carolyn Noor, Abdul Nygren, Gudrun Oliveira, Guiomar Papanikolaou, Katerina Parr, Jeremy R. Parrini, Barbara Paton, Tara Pickles, Andrew Piven, Joseph Posey, David J Poustka, Annemarie Poustka, Fritz Prasad, Aparna Ragoussis, Jiannis Renshaw, Katy Rickaby, Jessica Roberts, Wendy Roeder, Kathryn Roge, Bernadette Rutter, Michael L. Bierut, Laura J. Rice, John P. Salt, Jeff Sansom, Katherine Sato, Daisuke Segurado, Ricardo Senman, Lili Shah, Naisha Sheffield, Val C. Soorya, Latha Sousa, Inês Stoppioni, Vera Strawbridge, Christina Tancredi, Raffaella Tansey, Katherine Thiruvahindrapduram, Bhooma Thompson, Ann P. Thomson, Susanne Tryfon, Ana Tsiantis, John Van Engeland, Herman Vincent, John B. Volkmar, Fred Wallace, Simon Wang, Kai Wang, Zhouzhi Wassink, Thomas H. Wing, Kirsty Wittemeyer, Kerstin Wood, Shawn Yaspan, Brian L. Zurawiecki, Danielle Zwaigenbaum, Lonnie Betancur, Catalina Buxbaum, Joseph D. Cantor, Rita M. Cook, Edwin H. Coon, Hilary Cuccaro, Michael L. Gallagher, Louise Geschwind, Daniel H. Gill, Michael Haines, Jonathan L. Miller, Judith Monaco, Anthony P. Nurnberger, John I. Paterson, Andrew D. Pericak-Vance, Margaret A. Schellenberg, Gerard D. Scherer, Stephen W. Sutcliffe, James S. Szatmari, Peter Vicente, Astrid M. Vieland, Veronica J. Wijsman, Ellen M. Devlin, Bernie Ennis, Sean Hallmayer, Joachim |
| author_facet | Anney, Richard Klei, Lambertus Pinto, Dalila Regan, Regina Conroy, Judith Magalhaes, Tiago R. Correia, Catarina Abrahams, Brett S. Sykes, Nuala Pagnamenta, Alistair T. Almeida, Joana Bacchelli, Elena Bailey, Anthony J. Baird, Gillian Battaglia, Agatino Berney, Tom Bolshakova, Nadia Bölte, Sven Bolton, Patrick F. Bourgeron, Thomas Brennan, Sean Brian, Jessica Carson, Andrew R. Casallo, Guillermo Casey, Jillian Chu, Su H. Cochrane, Lynne Corsello, Christina Crawford, Emily L. Crossett, Andrew Dawson, Geraldine de Jonge, Maretha Delorme, Richard Drmic, Irene Duketis, Eftichia Duque, Frederico Estes, Annette Farrar, Penny Fernandez, Bridget A. Folstein, Susan E. Fombonne, Eric Freitag, Christine M. Gilbert, John Gillberg, Christopher Glessner, Joseph T. Goldberg, Jeremy Green, Jonathan Guter, Stephen J. Hakonarson, Hakon Heron, Elizabeth A. Hill, Matthew Holt, Richard Howe, Jennifer L. Hughes, Gillian Hus, Vanessa Igliozzi, Roberta Kim, Cecilia Klauck, Sabine M. Kolevzon, Alexander Korvatska, Olena Kustanovich, Vlad Lajonchere, Clara M. Lamb, Janine A. Laskawiec, Magdalena Leboyer, Marion Le Couteur, Ann Leventhal, Bennett L. Lionel, Anath C. Liu, Xiao-Qing Lord, Catherine Lotspeich, Linda Lund, Sabata C. Maestrini, Elena Mahoney, William Mantoulan, Carine Marshall, Christian R. McConachie, Helen McDougle, Christopher J. McGrath, Jane McMahon, William M. Melhem, Nadine M. Merikangas, Alison Migita, Ohsuke Minshew, Nancy J. Mirza, Ghazala K. Munson, Jeff Nelson, Stanley F. Noakes, Carolyn Noor, Abdul Nygren, Gudrun Oliveira, Guiomar Papanikolaou, Katerina Parr, Jeremy R. Parrini, Barbara Paton, Tara Pickles, Andrew Piven, Joseph Posey, David J Poustka, Annemarie Poustka, Fritz Prasad, Aparna Ragoussis, Jiannis Renshaw, Katy Rickaby, Jessica Roberts, Wendy Roeder, Kathryn Roge, Bernadette Rutter, Michael L. Bierut, Laura J. Rice, John P. Salt, Jeff Sansom, Katherine Sato, Daisuke Segurado, Ricardo Senman, Lili Shah, Naisha Sheffield, Val C. Soorya, Latha Sousa, Inês Stoppioni, Vera Strawbridge, Christina Tancredi, Raffaella Tansey, Katherine Thiruvahindrapduram, Bhooma Thompson, Ann P. Thomson, Susanne Tryfon, Ana Tsiantis, John Van Engeland, Herman Vincent, John B. Volkmar, Fred Wallace, Simon Wang, Kai Wang, Zhouzhi Wassink, Thomas H. Wing, Kirsty Wittemeyer, Kerstin Wood, Shawn Yaspan, Brian L. Zurawiecki, Danielle Zwaigenbaum, Lonnie Betancur, Catalina Buxbaum, Joseph D. Cantor, Rita M. Cook, Edwin H. Coon, Hilary Cuccaro, Michael L. Gallagher, Louise Geschwind, Daniel H. Gill, Michael Haines, Jonathan L. Miller, Judith Monaco, Anthony P. Nurnberger, John I. Paterson, Andrew D. Pericak-Vance, Margaret A. Schellenberg, Gerard D. Scherer, Stephen W. Sutcliffe, James S. Szatmari, Peter Vicente, Astrid M. Vieland, Veronica J. Wijsman, Ellen M. Devlin, Bernie Ennis, Sean Hallmayer, Joachim |
| author_sort | Anney, Richard |
| collection | PubMed |
| description | Although autism spectrum disorders (ASDs) have a substantial genetic basis, most of the known genetic risk has been traced to rare variants, principally copy number variants (CNVs). To identify common risk variation, the Autism Genome Project (AGP) Consortium genotyped 1558 rigorously defined ASD families for 1 million single-nucleotide polymorphisms (SNPs) and analyzed these SNP genotypes for association with ASD. In one of four primary association analyses, the association signal for marker rs4141463, located within MACROD2, crossed the genome-wide association significance threshold of P < 5 × 10(−8). When a smaller replication sample was analyzed, the risk allele at rs4141463 was again over-transmitted; yet, consistent with the winner's curse, its effect size in the replication sample was much smaller; and, for the combined samples, the association signal barely fell below the P < 5 × 10(−8) threshold. Exploratory analyses of phenotypic subtypes yielded no significant associations after correction for multiple testing. They did, however, yield strong signals within several genes, KIAA0564, PLD5, POU6F2, ST8SIA2 and TAF1C. |
| format | Text |
| id | pubmed-2947401 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2010 |
| publisher | Oxford University Press |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-29474012010-10-04 A genome-wide scan for common alleles affecting risk for autism Anney, Richard Klei, Lambertus Pinto, Dalila Regan, Regina Conroy, Judith Magalhaes, Tiago R. Correia, Catarina Abrahams, Brett S. Sykes, Nuala Pagnamenta, Alistair T. Almeida, Joana Bacchelli, Elena Bailey, Anthony J. Baird, Gillian Battaglia, Agatino Berney, Tom Bolshakova, Nadia Bölte, Sven Bolton, Patrick F. Bourgeron, Thomas Brennan, Sean Brian, Jessica Carson, Andrew R. Casallo, Guillermo Casey, Jillian Chu, Su H. Cochrane, Lynne Corsello, Christina Crawford, Emily L. Crossett, Andrew Dawson, Geraldine de Jonge, Maretha Delorme, Richard Drmic, Irene Duketis, Eftichia Duque, Frederico Estes, Annette Farrar, Penny Fernandez, Bridget A. Folstein, Susan E. Fombonne, Eric Freitag, Christine M. Gilbert, John Gillberg, Christopher Glessner, Joseph T. Goldberg, Jeremy Green, Jonathan Guter, Stephen J. Hakonarson, Hakon Heron, Elizabeth A. Hill, Matthew Holt, Richard Howe, Jennifer L. Hughes, Gillian Hus, Vanessa Igliozzi, Roberta Kim, Cecilia Klauck, Sabine M. Kolevzon, Alexander Korvatska, Olena Kustanovich, Vlad Lajonchere, Clara M. Lamb, Janine A. Laskawiec, Magdalena Leboyer, Marion Le Couteur, Ann Leventhal, Bennett L. Lionel, Anath C. Liu, Xiao-Qing Lord, Catherine Lotspeich, Linda Lund, Sabata C. Maestrini, Elena Mahoney, William Mantoulan, Carine Marshall, Christian R. McConachie, Helen McDougle, Christopher J. McGrath, Jane McMahon, William M. Melhem, Nadine M. Merikangas, Alison Migita, Ohsuke Minshew, Nancy J. Mirza, Ghazala K. Munson, Jeff Nelson, Stanley F. Noakes, Carolyn Noor, Abdul Nygren, Gudrun Oliveira, Guiomar Papanikolaou, Katerina Parr, Jeremy R. Parrini, Barbara Paton, Tara Pickles, Andrew Piven, Joseph Posey, David J Poustka, Annemarie Poustka, Fritz Prasad, Aparna Ragoussis, Jiannis Renshaw, Katy Rickaby, Jessica Roberts, Wendy Roeder, Kathryn Roge, Bernadette Rutter, Michael L. Bierut, Laura J. Rice, John P. Salt, Jeff Sansom, Katherine Sato, Daisuke Segurado, Ricardo Senman, Lili Shah, Naisha Sheffield, Val C. Soorya, Latha Sousa, Inês Stoppioni, Vera Strawbridge, Christina Tancredi, Raffaella Tansey, Katherine Thiruvahindrapduram, Bhooma Thompson, Ann P. Thomson, Susanne Tryfon, Ana Tsiantis, John Van Engeland, Herman Vincent, John B. Volkmar, Fred Wallace, Simon Wang, Kai Wang, Zhouzhi Wassink, Thomas H. Wing, Kirsty Wittemeyer, Kerstin Wood, Shawn Yaspan, Brian L. Zurawiecki, Danielle Zwaigenbaum, Lonnie Betancur, Catalina Buxbaum, Joseph D. Cantor, Rita M. Cook, Edwin H. Coon, Hilary Cuccaro, Michael L. Gallagher, Louise Geschwind, Daniel H. Gill, Michael Haines, Jonathan L. Miller, Judith Monaco, Anthony P. Nurnberger, John I. Paterson, Andrew D. Pericak-Vance, Margaret A. Schellenberg, Gerard D. Scherer, Stephen W. Sutcliffe, James S. Szatmari, Peter Vicente, Astrid M. Vieland, Veronica J. Wijsman, Ellen M. Devlin, Bernie Ennis, Sean Hallmayer, Joachim Hum Mol Genet Association Studies Articles Although autism spectrum disorders (ASDs) have a substantial genetic basis, most of the known genetic risk has been traced to rare variants, principally copy number variants (CNVs). To identify common risk variation, the Autism Genome Project (AGP) Consortium genotyped 1558 rigorously defined ASD families for 1 million single-nucleotide polymorphisms (SNPs) and analyzed these SNP genotypes for association with ASD. In one of four primary association analyses, the association signal for marker rs4141463, located within MACROD2, crossed the genome-wide association significance threshold of P < 5 × 10(−8). When a smaller replication sample was analyzed, the risk allele at rs4141463 was again over-transmitted; yet, consistent with the winner's curse, its effect size in the replication sample was much smaller; and, for the combined samples, the association signal barely fell below the P < 5 × 10(−8) threshold. Exploratory analyses of phenotypic subtypes yielded no significant associations after correction for multiple testing. They did, however, yield strong signals within several genes, KIAA0564, PLD5, POU6F2, ST8SIA2 and TAF1C. Oxford University Press 2010-10-15 2010-07-27 /pmc/articles/PMC2947401/ /pubmed/20663923 http://dx.doi.org/10.1093/hmg/ddq307 Text en © The Author 2010. Published by Oxford University Press http://creativecommons.org/licenses/by-nc/2.5/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.5), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
| spellingShingle | Association Studies Articles Anney, Richard Klei, Lambertus Pinto, Dalila Regan, Regina Conroy, Judith Magalhaes, Tiago R. Correia, Catarina Abrahams, Brett S. Sykes, Nuala Pagnamenta, Alistair T. Almeida, Joana Bacchelli, Elena Bailey, Anthony J. Baird, Gillian Battaglia, Agatino Berney, Tom Bolshakova, Nadia Bölte, Sven Bolton, Patrick F. Bourgeron, Thomas Brennan, Sean Brian, Jessica Carson, Andrew R. Casallo, Guillermo Casey, Jillian Chu, Su H. Cochrane, Lynne Corsello, Christina Crawford, Emily L. Crossett, Andrew Dawson, Geraldine de Jonge, Maretha Delorme, Richard Drmic, Irene Duketis, Eftichia Duque, Frederico Estes, Annette Farrar, Penny Fernandez, Bridget A. Folstein, Susan E. Fombonne, Eric Freitag, Christine M. Gilbert, John Gillberg, Christopher Glessner, Joseph T. Goldberg, Jeremy Green, Jonathan Guter, Stephen J. Hakonarson, Hakon Heron, Elizabeth A. Hill, Matthew Holt, Richard Howe, Jennifer L. Hughes, Gillian Hus, Vanessa Igliozzi, Roberta Kim, Cecilia Klauck, Sabine M. Kolevzon, Alexander Korvatska, Olena Kustanovich, Vlad Lajonchere, Clara M. Lamb, Janine A. Laskawiec, Magdalena Leboyer, Marion Le Couteur, Ann Leventhal, Bennett L. Lionel, Anath C. Liu, Xiao-Qing Lord, Catherine Lotspeich, Linda Lund, Sabata C. Maestrini, Elena Mahoney, William Mantoulan, Carine Marshall, Christian R. McConachie, Helen McDougle, Christopher J. McGrath, Jane McMahon, William M. Melhem, Nadine M. Merikangas, Alison Migita, Ohsuke Minshew, Nancy J. Mirza, Ghazala K. Munson, Jeff Nelson, Stanley F. Noakes, Carolyn Noor, Abdul Nygren, Gudrun Oliveira, Guiomar Papanikolaou, Katerina Parr, Jeremy R. Parrini, Barbara Paton, Tara Pickles, Andrew Piven, Joseph Posey, David J Poustka, Annemarie Poustka, Fritz Prasad, Aparna Ragoussis, Jiannis Renshaw, Katy Rickaby, Jessica Roberts, Wendy Roeder, Kathryn Roge, Bernadette Rutter, Michael L. Bierut, Laura J. Rice, John P. Salt, Jeff Sansom, Katherine Sato, Daisuke Segurado, Ricardo Senman, Lili Shah, Naisha Sheffield, Val C. Soorya, Latha Sousa, Inês Stoppioni, Vera Strawbridge, Christina Tancredi, Raffaella Tansey, Katherine Thiruvahindrapduram, Bhooma Thompson, Ann P. Thomson, Susanne Tryfon, Ana Tsiantis, John Van Engeland, Herman Vincent, John B. Volkmar, Fred Wallace, Simon Wang, Kai Wang, Zhouzhi Wassink, Thomas H. Wing, Kirsty Wittemeyer, Kerstin Wood, Shawn Yaspan, Brian L. Zurawiecki, Danielle Zwaigenbaum, Lonnie Betancur, Catalina Buxbaum, Joseph D. Cantor, Rita M. Cook, Edwin H. Coon, Hilary Cuccaro, Michael L. Gallagher, Louise Geschwind, Daniel H. Gill, Michael Haines, Jonathan L. Miller, Judith Monaco, Anthony P. Nurnberger, John I. Paterson, Andrew D. Pericak-Vance, Margaret A. Schellenberg, Gerard D. Scherer, Stephen W. Sutcliffe, James S. Szatmari, Peter Vicente, Astrid M. Vieland, Veronica J. Wijsman, Ellen M. Devlin, Bernie Ennis, Sean Hallmayer, Joachim A genome-wide scan for common alleles affecting risk for autism |
| title | A genome-wide scan for common alleles affecting risk for autism |
| title_full | A genome-wide scan for common alleles affecting risk for autism |
| title_fullStr | A genome-wide scan for common alleles affecting risk for autism |
| title_full_unstemmed | A genome-wide scan for common alleles affecting risk for autism |
| title_short | A genome-wide scan for common alleles affecting risk for autism |
| title_sort | genome-wide scan for common alleles affecting risk for autism |
| topic | Association Studies Articles |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2947401/ https://www.ncbi.nlm.nih.gov/pubmed/20663923 http://dx.doi.org/10.1093/hmg/ddq307 |
| work_keys_str_mv | AT anneyrichard agenomewidescanforcommonallelesaffectingriskforautism AT kleilambertus agenomewidescanforcommonallelesaffectingriskforautism AT pintodalila agenomewidescanforcommonallelesaffectingriskforautism AT reganregina agenomewidescanforcommonallelesaffectingriskforautism AT conroyjudith agenomewidescanforcommonallelesaffectingriskforautism AT magalhaestiagor agenomewidescanforcommonallelesaffectingriskforautism AT correiacatarina agenomewidescanforcommonallelesaffectingriskforautism AT abrahamsbretts agenomewidescanforcommonallelesaffectingriskforautism AT sykesnuala agenomewidescanforcommonallelesaffectingriskforautism AT pagnamentaalistairt agenomewidescanforcommonallelesaffectingriskforautism AT almeidajoana agenomewidescanforcommonallelesaffectingriskforautism AT bacchellielena agenomewidescanforcommonallelesaffectingriskforautism AT baileyanthonyj agenomewidescanforcommonallelesaffectingriskforautism AT bairdgillian agenomewidescanforcommonallelesaffectingriskforautism AT battagliaagatino agenomewidescanforcommonallelesaffectingriskforautism AT berneytom agenomewidescanforcommonallelesaffectingriskforautism AT bolshakovanadia agenomewidescanforcommonallelesaffectingriskforautism AT boltesven agenomewidescanforcommonallelesaffectingriskforautism AT boltonpatrickf agenomewidescanforcommonallelesaffectingriskforautism AT bourgeronthomas agenomewidescanforcommonallelesaffectingriskforautism AT brennansean agenomewidescanforcommonallelesaffectingriskforautism AT brianjessica agenomewidescanforcommonallelesaffectingriskforautism AT carsonandrewr agenomewidescanforcommonallelesaffectingriskforautism AT casalloguillermo agenomewidescanforcommonallelesaffectingriskforautism AT caseyjillian agenomewidescanforcommonallelesaffectingriskforautism AT chusuh agenomewidescanforcommonallelesaffectingriskforautism AT cochranelynne agenomewidescanforcommonallelesaffectingriskforautism AT corsellochristina agenomewidescanforcommonallelesaffectingriskforautism AT crawfordemilyl agenomewidescanforcommonallelesaffectingriskforautism AT crossettandrew agenomewidescanforcommonallelesaffectingriskforautism AT dawsongeraldine agenomewidescanforcommonallelesaffectingriskforautism AT dejongemaretha agenomewidescanforcommonallelesaffectingriskforautism AT delormerichard agenomewidescanforcommonallelesaffectingriskforautism AT drmicirene agenomewidescanforcommonallelesaffectingriskforautism AT duketiseftichia agenomewidescanforcommonallelesaffectingriskforautism AT duquefrederico agenomewidescanforcommonallelesaffectingriskforautism AT estesannette agenomewidescanforcommonallelesaffectingriskforautism AT farrarpenny agenomewidescanforcommonallelesaffectingriskforautism AT fernandezbridgeta agenomewidescanforcommonallelesaffectingriskforautism AT folsteinsusane agenomewidescanforcommonallelesaffectingriskforautism AT fombonneeric agenomewidescanforcommonallelesaffectingriskforautism AT freitagchristinem agenomewidescanforcommonallelesaffectingriskforautism AT gilbertjohn agenomewidescanforcommonallelesaffectingriskforautism AT gillbergchristopher agenomewidescanforcommonallelesaffectingriskforautism AT glessnerjosepht agenomewidescanforcommonallelesaffectingriskforautism AT goldbergjeremy agenomewidescanforcommonallelesaffectingriskforautism AT greenjonathan agenomewidescanforcommonallelesaffectingriskforautism AT guterstephenj agenomewidescanforcommonallelesaffectingriskforautism AT hakonarsonhakon agenomewidescanforcommonallelesaffectingriskforautism AT heronelizabetha agenomewidescanforcommonallelesaffectingriskforautism AT hillmatthew agenomewidescanforcommonallelesaffectingriskforautism AT holtrichard agenomewidescanforcommonallelesaffectingriskforautism AT howejenniferl agenomewidescanforcommonallelesaffectingriskforautism AT hughesgillian agenomewidescanforcommonallelesaffectingriskforautism AT husvanessa agenomewidescanforcommonallelesaffectingriskforautism AT igliozziroberta agenomewidescanforcommonallelesaffectingriskforautism AT kimcecilia agenomewidescanforcommonallelesaffectingriskforautism AT klaucksabinem agenomewidescanforcommonallelesaffectingriskforautism AT kolevzonalexander agenomewidescanforcommonallelesaffectingriskforautism AT korvatskaolena agenomewidescanforcommonallelesaffectingriskforautism AT kustanovichvlad agenomewidescanforcommonallelesaffectingriskforautism AT lajonchereclaram agenomewidescanforcommonallelesaffectingriskforautism AT lambjaninea agenomewidescanforcommonallelesaffectingriskforautism AT laskawiecmagdalena agenomewidescanforcommonallelesaffectingriskforautism AT leboyermarion agenomewidescanforcommonallelesaffectingriskforautism AT lecouteurann agenomewidescanforcommonallelesaffectingriskforautism AT leventhalbennettl agenomewidescanforcommonallelesaffectingriskforautism AT lionelanathc agenomewidescanforcommonallelesaffectingriskforautism AT liuxiaoqing agenomewidescanforcommonallelesaffectingriskforautism AT lordcatherine agenomewidescanforcommonallelesaffectingriskforautism AT lotspeichlinda agenomewidescanforcommonallelesaffectingriskforautism AT lundsabatac agenomewidescanforcommonallelesaffectingriskforautism AT maestrinielena agenomewidescanforcommonallelesaffectingriskforautism AT mahoneywilliam agenomewidescanforcommonallelesaffectingriskforautism AT mantoulancarine agenomewidescanforcommonallelesaffectingriskforautism AT marshallchristianr agenomewidescanforcommonallelesaffectingriskforautism AT mcconachiehelen agenomewidescanforcommonallelesaffectingriskforautism AT mcdouglechristopherj agenomewidescanforcommonallelesaffectingriskforautism AT mcgrathjane agenomewidescanforcommonallelesaffectingriskforautism AT mcmahonwilliamm agenomewidescanforcommonallelesaffectingriskforautism AT melhemnadinem agenomewidescanforcommonallelesaffectingriskforautism AT merikangasalison agenomewidescanforcommonallelesaffectingriskforautism AT migitaohsuke agenomewidescanforcommonallelesaffectingriskforautism AT minshewnancyj agenomewidescanforcommonallelesaffectingriskforautism AT mirzaghazalak agenomewidescanforcommonallelesaffectingriskforautism AT munsonjeff agenomewidescanforcommonallelesaffectingriskforautism AT nelsonstanleyf agenomewidescanforcommonallelesaffectingriskforautism AT noakescarolyn agenomewidescanforcommonallelesaffectingriskforautism AT noorabdul agenomewidescanforcommonallelesaffectingriskforautism AT nygrengudrun agenomewidescanforcommonallelesaffectingriskforautism AT oliveiraguiomar agenomewidescanforcommonallelesaffectingriskforautism AT papanikolaoukaterina agenomewidescanforcommonallelesaffectingriskforautism AT parrjeremyr agenomewidescanforcommonallelesaffectingriskforautism AT parrinibarbara agenomewidescanforcommonallelesaffectingriskforautism AT patontara agenomewidescanforcommonallelesaffectingriskforautism AT picklesandrew agenomewidescanforcommonallelesaffectingriskforautism AT pivenjoseph agenomewidescanforcommonallelesaffectingriskforautism AT poseydavidj agenomewidescanforcommonallelesaffectingriskforautism AT poustkaannemarie agenomewidescanforcommonallelesaffectingriskforautism AT poustkafritz agenomewidescanforcommonallelesaffectingriskforautism AT prasadaparna agenomewidescanforcommonallelesaffectingriskforautism AT ragoussisjiannis agenomewidescanforcommonallelesaffectingriskforautism AT renshawkaty agenomewidescanforcommonallelesaffectingriskforautism AT rickabyjessica agenomewidescanforcommonallelesaffectingriskforautism AT robertswendy agenomewidescanforcommonallelesaffectingriskforautism AT roederkathryn agenomewidescanforcommonallelesaffectingriskforautism AT rogebernadette agenomewidescanforcommonallelesaffectingriskforautism AT ruttermichaell agenomewidescanforcommonallelesaffectingriskforautism AT bierutlauraj agenomewidescanforcommonallelesaffectingriskforautism AT ricejohnp agenomewidescanforcommonallelesaffectingriskforautism AT saltjeff agenomewidescanforcommonallelesaffectingriskforautism AT sansomkatherine agenomewidescanforcommonallelesaffectingriskforautism AT satodaisuke agenomewidescanforcommonallelesaffectingriskforautism AT seguradoricardo agenomewidescanforcommonallelesaffectingriskforautism AT senmanlili agenomewidescanforcommonallelesaffectingriskforautism AT shahnaisha agenomewidescanforcommonallelesaffectingriskforautism AT sheffieldvalc agenomewidescanforcommonallelesaffectingriskforautism AT sooryalatha agenomewidescanforcommonallelesaffectingriskforautism AT sousaines agenomewidescanforcommonallelesaffectingriskforautism AT stoppionivera agenomewidescanforcommonallelesaffectingriskforautism AT strawbridgechristina agenomewidescanforcommonallelesaffectingriskforautism AT tancrediraffaella agenomewidescanforcommonallelesaffectingriskforautism AT tanseykatherine agenomewidescanforcommonallelesaffectingriskforautism AT thiruvahindrapdurambhooma agenomewidescanforcommonallelesaffectingriskforautism AT thompsonannp agenomewidescanforcommonallelesaffectingriskforautism AT thomsonsusanne agenomewidescanforcommonallelesaffectingriskforautism AT tryfonana agenomewidescanforcommonallelesaffectingriskforautism AT tsiantisjohn agenomewidescanforcommonallelesaffectingriskforautism AT vanengelandherman agenomewidescanforcommonallelesaffectingriskforautism AT vincentjohnb agenomewidescanforcommonallelesaffectingriskforautism AT volkmarfred agenomewidescanforcommonallelesaffectingriskforautism AT wallacesimon agenomewidescanforcommonallelesaffectingriskforautism AT wangkai agenomewidescanforcommonallelesaffectingriskforautism AT wangzhouzhi agenomewidescanforcommonallelesaffectingriskforautism AT wassinkthomash agenomewidescanforcommonallelesaffectingriskforautism AT wingkirsty agenomewidescanforcommonallelesaffectingriskforautism AT wittemeyerkerstin agenomewidescanforcommonallelesaffectingriskforautism AT woodshawn agenomewidescanforcommonallelesaffectingriskforautism AT yaspanbrianl agenomewidescanforcommonallelesaffectingriskforautism AT zurawieckidanielle agenomewidescanforcommonallelesaffectingriskforautism AT zwaigenbaumlonnie agenomewidescanforcommonallelesaffectingriskforautism AT betancurcatalina agenomewidescanforcommonallelesaffectingriskforautism AT buxbaumjosephd agenomewidescanforcommonallelesaffectingriskforautism AT cantorritam agenomewidescanforcommonallelesaffectingriskforautism AT cookedwinh agenomewidescanforcommonallelesaffectingriskforautism AT coonhilary agenomewidescanforcommonallelesaffectingriskforautism AT cuccaromichaell agenomewidescanforcommonallelesaffectingriskforautism AT gallagherlouise agenomewidescanforcommonallelesaffectingriskforautism AT geschwinddanielh agenomewidescanforcommonallelesaffectingriskforautism AT gillmichael agenomewidescanforcommonallelesaffectingriskforautism AT hainesjonathanl agenomewidescanforcommonallelesaffectingriskforautism AT millerjudith agenomewidescanforcommonallelesaffectingriskforautism AT monacoanthonyp agenomewidescanforcommonallelesaffectingriskforautism AT nurnbergerjohni agenomewidescanforcommonallelesaffectingriskforautism AT patersonandrewd agenomewidescanforcommonallelesaffectingriskforautism AT pericakvancemargareta agenomewidescanforcommonallelesaffectingriskforautism AT schellenberggerardd agenomewidescanforcommonallelesaffectingriskforautism AT schererstephenw agenomewidescanforcommonallelesaffectingriskforautism AT sutcliffejamess agenomewidescanforcommonallelesaffectingriskforautism AT szatmaripeter agenomewidescanforcommonallelesaffectingriskforautism AT vicenteastridm agenomewidescanforcommonallelesaffectingriskforautism AT vielandveronicaj agenomewidescanforcommonallelesaffectingriskforautism AT wijsmanellenm agenomewidescanforcommonallelesaffectingriskforautism AT devlinbernie agenomewidescanforcommonallelesaffectingriskforautism AT ennissean agenomewidescanforcommonallelesaffectingriskforautism AT hallmayerjoachim agenomewidescanforcommonallelesaffectingriskforautism AT anneyrichard genomewidescanforcommonallelesaffectingriskforautism AT kleilambertus genomewidescanforcommonallelesaffectingriskforautism AT pintodalila genomewidescanforcommonallelesaffectingriskforautism AT reganregina genomewidescanforcommonallelesaffectingriskforautism AT conroyjudith genomewidescanforcommonallelesaffectingriskforautism AT magalhaestiagor genomewidescanforcommonallelesaffectingriskforautism AT correiacatarina genomewidescanforcommonallelesaffectingriskforautism AT abrahamsbretts genomewidescanforcommonallelesaffectingriskforautism AT sykesnuala genomewidescanforcommonallelesaffectingriskforautism AT pagnamentaalistairt genomewidescanforcommonallelesaffectingriskforautism AT almeidajoana genomewidescanforcommonallelesaffectingriskforautism AT bacchellielena genomewidescanforcommonallelesaffectingriskforautism AT baileyanthonyj genomewidescanforcommonallelesaffectingriskforautism AT bairdgillian genomewidescanforcommonallelesaffectingriskforautism AT battagliaagatino genomewidescanforcommonallelesaffectingriskforautism AT berneytom genomewidescanforcommonallelesaffectingriskforautism AT bolshakovanadia genomewidescanforcommonallelesaffectingriskforautism AT boltesven genomewidescanforcommonallelesaffectingriskforautism AT boltonpatrickf genomewidescanforcommonallelesaffectingriskforautism AT bourgeronthomas genomewidescanforcommonallelesaffectingriskforautism AT brennansean genomewidescanforcommonallelesaffectingriskforautism AT brianjessica genomewidescanforcommonallelesaffectingriskforautism AT carsonandrewr genomewidescanforcommonallelesaffectingriskforautism AT casalloguillermo genomewidescanforcommonallelesaffectingriskforautism AT caseyjillian genomewidescanforcommonallelesaffectingriskforautism AT chusuh genomewidescanforcommonallelesaffectingriskforautism AT cochranelynne genomewidescanforcommonallelesaffectingriskforautism AT corsellochristina genomewidescanforcommonallelesaffectingriskforautism AT crawfordemilyl genomewidescanforcommonallelesaffectingriskforautism AT crossettandrew genomewidescanforcommonallelesaffectingriskforautism AT dawsongeraldine genomewidescanforcommonallelesaffectingriskforautism AT dejongemaretha genomewidescanforcommonallelesaffectingriskforautism AT delormerichard genomewidescanforcommonallelesaffectingriskforautism AT drmicirene genomewidescanforcommonallelesaffectingriskforautism AT duketiseftichia genomewidescanforcommonallelesaffectingriskforautism AT duquefrederico genomewidescanforcommonallelesaffectingriskforautism AT estesannette genomewidescanforcommonallelesaffectingriskforautism AT farrarpenny genomewidescanforcommonallelesaffectingriskforautism AT fernandezbridgeta genomewidescanforcommonallelesaffectingriskforautism AT folsteinsusane genomewidescanforcommonallelesaffectingriskforautism AT fombonneeric genomewidescanforcommonallelesaffectingriskforautism AT freitagchristinem genomewidescanforcommonallelesaffectingriskforautism AT gilbertjohn genomewidescanforcommonallelesaffectingriskforautism AT gillbergchristopher genomewidescanforcommonallelesaffectingriskforautism AT glessnerjosepht genomewidescanforcommonallelesaffectingriskforautism AT goldbergjeremy genomewidescanforcommonallelesaffectingriskforautism AT greenjonathan genomewidescanforcommonallelesaffectingriskforautism AT guterstephenj genomewidescanforcommonallelesaffectingriskforautism AT hakonarsonhakon genomewidescanforcommonallelesaffectingriskforautism AT heronelizabetha genomewidescanforcommonallelesaffectingriskforautism AT hillmatthew genomewidescanforcommonallelesaffectingriskforautism AT holtrichard genomewidescanforcommonallelesaffectingriskforautism AT howejenniferl genomewidescanforcommonallelesaffectingriskforautism AT hughesgillian genomewidescanforcommonallelesaffectingriskforautism AT husvanessa genomewidescanforcommonallelesaffectingriskforautism AT igliozziroberta genomewidescanforcommonallelesaffectingriskforautism AT kimcecilia genomewidescanforcommonallelesaffectingriskforautism AT klaucksabinem genomewidescanforcommonallelesaffectingriskforautism AT kolevzonalexander genomewidescanforcommonallelesaffectingriskforautism AT korvatskaolena genomewidescanforcommonallelesaffectingriskforautism AT kustanovichvlad genomewidescanforcommonallelesaffectingriskforautism AT lajonchereclaram genomewidescanforcommonallelesaffectingriskforautism AT lambjaninea genomewidescanforcommonallelesaffectingriskforautism AT laskawiecmagdalena genomewidescanforcommonallelesaffectingriskforautism AT leboyermarion genomewidescanforcommonallelesaffectingriskforautism AT lecouteurann genomewidescanforcommonallelesaffectingriskforautism AT leventhalbennettl genomewidescanforcommonallelesaffectingriskforautism AT lionelanathc genomewidescanforcommonallelesaffectingriskforautism AT liuxiaoqing genomewidescanforcommonallelesaffectingriskforautism AT lordcatherine genomewidescanforcommonallelesaffectingriskforautism AT lotspeichlinda genomewidescanforcommonallelesaffectingriskforautism AT lundsabatac genomewidescanforcommonallelesaffectingriskforautism AT maestrinielena genomewidescanforcommonallelesaffectingriskforautism AT mahoneywilliam genomewidescanforcommonallelesaffectingriskforautism AT mantoulancarine genomewidescanforcommonallelesaffectingriskforautism AT marshallchristianr genomewidescanforcommonallelesaffectingriskforautism AT mcconachiehelen genomewidescanforcommonallelesaffectingriskforautism AT mcdouglechristopherj genomewidescanforcommonallelesaffectingriskforautism AT mcgrathjane genomewidescanforcommonallelesaffectingriskforautism AT mcmahonwilliamm genomewidescanforcommonallelesaffectingriskforautism AT melhemnadinem genomewidescanforcommonallelesaffectingriskforautism AT merikangasalison genomewidescanforcommonallelesaffectingriskforautism AT migitaohsuke genomewidescanforcommonallelesaffectingriskforautism AT minshewnancyj genomewidescanforcommonallelesaffectingriskforautism AT mirzaghazalak genomewidescanforcommonallelesaffectingriskforautism AT munsonjeff genomewidescanforcommonallelesaffectingriskforautism AT nelsonstanleyf genomewidescanforcommonallelesaffectingriskforautism AT noakescarolyn genomewidescanforcommonallelesaffectingriskforautism AT noorabdul genomewidescanforcommonallelesaffectingriskforautism AT nygrengudrun genomewidescanforcommonallelesaffectingriskforautism AT oliveiraguiomar genomewidescanforcommonallelesaffectingriskforautism AT papanikolaoukaterina genomewidescanforcommonallelesaffectingriskforautism AT parrjeremyr genomewidescanforcommonallelesaffectingriskforautism AT parrinibarbara genomewidescanforcommonallelesaffectingriskforautism AT patontara genomewidescanforcommonallelesaffectingriskforautism AT picklesandrew genomewidescanforcommonallelesaffectingriskforautism AT pivenjoseph genomewidescanforcommonallelesaffectingriskforautism AT poseydavidj genomewidescanforcommonallelesaffectingriskforautism AT poustkaannemarie genomewidescanforcommonallelesaffectingriskforautism AT poustkafritz genomewidescanforcommonallelesaffectingriskforautism AT prasadaparna genomewidescanforcommonallelesaffectingriskforautism AT ragoussisjiannis genomewidescanforcommonallelesaffectingriskforautism AT renshawkaty genomewidescanforcommonallelesaffectingriskforautism AT rickabyjessica genomewidescanforcommonallelesaffectingriskforautism AT robertswendy genomewidescanforcommonallelesaffectingriskforautism AT roederkathryn genomewidescanforcommonallelesaffectingriskforautism AT rogebernadette genomewidescanforcommonallelesaffectingriskforautism AT ruttermichaell genomewidescanforcommonallelesaffectingriskforautism AT bierutlauraj genomewidescanforcommonallelesaffectingriskforautism AT ricejohnp genomewidescanforcommonallelesaffectingriskforautism AT saltjeff genomewidescanforcommonallelesaffectingriskforautism AT sansomkatherine genomewidescanforcommonallelesaffectingriskforautism AT satodaisuke genomewidescanforcommonallelesaffectingriskforautism AT seguradoricardo genomewidescanforcommonallelesaffectingriskforautism AT senmanlili genomewidescanforcommonallelesaffectingriskforautism AT shahnaisha genomewidescanforcommonallelesaffectingriskforautism AT sheffieldvalc genomewidescanforcommonallelesaffectingriskforautism AT sooryalatha genomewidescanforcommonallelesaffectingriskforautism AT sousaines genomewidescanforcommonallelesaffectingriskforautism AT stoppionivera genomewidescanforcommonallelesaffectingriskforautism AT strawbridgechristina genomewidescanforcommonallelesaffectingriskforautism AT tancrediraffaella genomewidescanforcommonallelesaffectingriskforautism AT tanseykatherine genomewidescanforcommonallelesaffectingriskforautism AT thiruvahindrapdurambhooma genomewidescanforcommonallelesaffectingriskforautism AT thompsonannp genomewidescanforcommonallelesaffectingriskforautism AT thomsonsusanne genomewidescanforcommonallelesaffectingriskforautism AT tryfonana genomewidescanforcommonallelesaffectingriskforautism AT tsiantisjohn genomewidescanforcommonallelesaffectingriskforautism AT vanengelandherman genomewidescanforcommonallelesaffectingriskforautism AT vincentjohnb genomewidescanforcommonallelesaffectingriskforautism AT volkmarfred genomewidescanforcommonallelesaffectingriskforautism AT wallacesimon genomewidescanforcommonallelesaffectingriskforautism AT wangkai genomewidescanforcommonallelesaffectingriskforautism AT wangzhouzhi genomewidescanforcommonallelesaffectingriskforautism AT wassinkthomash genomewidescanforcommonallelesaffectingriskforautism AT wingkirsty genomewidescanforcommonallelesaffectingriskforautism AT wittemeyerkerstin genomewidescanforcommonallelesaffectingriskforautism AT woodshawn genomewidescanforcommonallelesaffectingriskforautism AT yaspanbrianl genomewidescanforcommonallelesaffectingriskforautism AT zurawieckidanielle genomewidescanforcommonallelesaffectingriskforautism AT zwaigenbaumlonnie genomewidescanforcommonallelesaffectingriskforautism AT betancurcatalina genomewidescanforcommonallelesaffectingriskforautism AT buxbaumjosephd genomewidescanforcommonallelesaffectingriskforautism AT cantorritam genomewidescanforcommonallelesaffectingriskforautism AT cookedwinh genomewidescanforcommonallelesaffectingriskforautism AT coonhilary genomewidescanforcommonallelesaffectingriskforautism AT cuccaromichaell genomewidescanforcommonallelesaffectingriskforautism AT gallagherlouise genomewidescanforcommonallelesaffectingriskforautism AT geschwinddanielh genomewidescanforcommonallelesaffectingriskforautism AT gillmichael genomewidescanforcommonallelesaffectingriskforautism AT hainesjonathanl genomewidescanforcommonallelesaffectingriskforautism AT millerjudith genomewidescanforcommonallelesaffectingriskforautism AT monacoanthonyp genomewidescanforcommonallelesaffectingriskforautism AT nurnbergerjohni genomewidescanforcommonallelesaffectingriskforautism AT patersonandrewd genomewidescanforcommonallelesaffectingriskforautism AT pericakvancemargareta genomewidescanforcommonallelesaffectingriskforautism AT schellenberggerardd genomewidescanforcommonallelesaffectingriskforautism AT schererstephenw genomewidescanforcommonallelesaffectingriskforautism AT sutcliffejamess genomewidescanforcommonallelesaffectingriskforautism AT szatmaripeter genomewidescanforcommonallelesaffectingriskforautism AT vicenteastridm genomewidescanforcommonallelesaffectingriskforautism AT vielandveronicaj genomewidescanforcommonallelesaffectingriskforautism AT wijsmanellenm genomewidescanforcommonallelesaffectingriskforautism AT devlinbernie genomewidescanforcommonallelesaffectingriskforautism AT ennissean genomewidescanforcommonallelesaffectingriskforautism AT hallmayerjoachim genomewidescanforcommonallelesaffectingriskforautism |