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ERBB4 PROMOTES CYCLOOXYGENASE-2 EXPRESSION AND CELL SURVIVAL IN COLON EPITHELIAL CELLS

The ErbB4 receptor tyrosine kinase is expressed at high levels in human and mouse colitis, and inhibits colon epithelial cell apoptosis in the presence of pro-inflammatory cytokines. In this study, we investigated the molecular mechanisms responsible for ErbB4-induced cell survival. In cultured mous...

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Detalles Bibliográficos
Autores principales:	Frey, Mark Ronald, Hilliard, Valda Catherine, Mullane, Matthew Travis, Polk, D. Brent
Formato:	Texto
Lenguaje:	English
Publicado:	2010
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2947587/ https://www.ncbi.nlm.nih.gov/pubmed/20585313 http://dx.doi.org/10.1038/labinvest.2010.117

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