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Cemented Endoprosthetic Reconstruction of the Proximal Tibia: How Long Do They Last?

BACKGROUND: The few available studies documenting the long-term survival of cemented proximal tibial endoprostheses for musculoskeletal tumors do not differentiate between stem designs or patient diagnosis. There is wide variation in survival rates reported, possibly a result of this heterogeneity i...

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Autores principales: Schwartz, Adam J., Kabo, J. Michael, Eilber, Fritz C., Eilber, Frederick R., Eckardt, Jeffrey J.
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2947676/
https://www.ncbi.nlm.nih.gov/pubmed/20495967
http://dx.doi.org/10.1007/s11999-010-1390-9
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author Schwartz, Adam J.
Kabo, J. Michael
Eilber, Fritz C.
Eilber, Frederick R.
Eckardt, Jeffrey J.
author_facet Schwartz, Adam J.
Kabo, J. Michael
Eilber, Fritz C.
Eilber, Frederick R.
Eckardt, Jeffrey J.
author_sort Schwartz, Adam J.
collection PubMed
description BACKGROUND: The few available studies documenting the long-term survival of cemented proximal tibial endoprostheses for musculoskeletal tumors do not differentiate between stem designs or patient diagnosis. There is wide variation in survival rates reported, possibly a result of this heterogeneity in patient population and implant design. QUESTIONS/PURPOSES: We therefore asked: (1) How long do proximal tibial endoprostheses last? (2) What is the typical long-term functional result after proximal tibial replacement? And (3) what are the short- and long-term complications associated with endoprosthetic reconstruction of the proximal tibia, particularly with respect to the soft tissue reconstruction? PATIENTS AND METHODS: We retrospectively reviewed 52 patients with 52 proximal tibial endoprosthetic reconstructions for a tumor-related diagnosis. Kaplan-Meier survivorship analysis was performed using revision of the stemmed components for any reason as an endpoint for implants, and death due to disease progression for patients. Function was assessed using the MSTS scoring system. The minimum followup was 1 month (mean, 96 months: range, 1–284 months; median, 69 months). RESULTS: Using revision of the stemmed components for any reason as an end point, overall prosthesis survival at 5, 10, 15, and 20 years was 94%, 86%, 66%, and 37%, respectively. The 29 modular implants demonstrated a trend toward improved survival compared to the 23 custom-designed components, with a 15-year survivorship of 88% versus 63%. The mean postoperative Musculoskeletal Tumor Society score at most recent followup was 82% of normal function (mean raw score, 24.6; range, 4–29). CONCLUSIONS: Cemented endoprosthetic reconstruction of the proximal tibia provides a reliable method of reconstruction following tumor resection. LEVEL OF EVIDENCE: Level IV, therapeutic study. See the Guidelines for Authors for a complete description of levels of evidence.
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spelling pubmed-29476762010-10-12 Cemented Endoprosthetic Reconstruction of the Proximal Tibia: How Long Do They Last? Schwartz, Adam J. Kabo, J. Michael Eilber, Fritz C. Eilber, Frederick R. Eckardt, Jeffrey J. Clin Orthop Relat Res Symposium: Highlights of the ISOLS/MSTS 2009 Meeting BACKGROUND: The few available studies documenting the long-term survival of cemented proximal tibial endoprostheses for musculoskeletal tumors do not differentiate between stem designs or patient diagnosis. There is wide variation in survival rates reported, possibly a result of this heterogeneity in patient population and implant design. QUESTIONS/PURPOSES: We therefore asked: (1) How long do proximal tibial endoprostheses last? (2) What is the typical long-term functional result after proximal tibial replacement? And (3) what are the short- and long-term complications associated with endoprosthetic reconstruction of the proximal tibia, particularly with respect to the soft tissue reconstruction? PATIENTS AND METHODS: We retrospectively reviewed 52 patients with 52 proximal tibial endoprosthetic reconstructions for a tumor-related diagnosis. Kaplan-Meier survivorship analysis was performed using revision of the stemmed components for any reason as an endpoint for implants, and death due to disease progression for patients. Function was assessed using the MSTS scoring system. The minimum followup was 1 month (mean, 96 months: range, 1–284 months; median, 69 months). RESULTS: Using revision of the stemmed components for any reason as an end point, overall prosthesis survival at 5, 10, 15, and 20 years was 94%, 86%, 66%, and 37%, respectively. The 29 modular implants demonstrated a trend toward improved survival compared to the 23 custom-designed components, with a 15-year survivorship of 88% versus 63%. The mean postoperative Musculoskeletal Tumor Society score at most recent followup was 82% of normal function (mean raw score, 24.6; range, 4–29). CONCLUSIONS: Cemented endoprosthetic reconstruction of the proximal tibia provides a reliable method of reconstruction following tumor resection. LEVEL OF EVIDENCE: Level IV, therapeutic study. See the Guidelines for Authors for a complete description of levels of evidence. Springer-Verlag 2010-05-22 2010-11 /pmc/articles/PMC2947676/ /pubmed/20495967 http://dx.doi.org/10.1007/s11999-010-1390-9 Text en © The Author(s) 2010 https://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited.
spellingShingle Symposium: Highlights of the ISOLS/MSTS 2009 Meeting
Schwartz, Adam J.
Kabo, J. Michael
Eilber, Fritz C.
Eilber, Frederick R.
Eckardt, Jeffrey J.
Cemented Endoprosthetic Reconstruction of the Proximal Tibia: How Long Do They Last?
title Cemented Endoprosthetic Reconstruction of the Proximal Tibia: How Long Do They Last?
title_full Cemented Endoprosthetic Reconstruction of the Proximal Tibia: How Long Do They Last?
title_fullStr Cemented Endoprosthetic Reconstruction of the Proximal Tibia: How Long Do They Last?
title_full_unstemmed Cemented Endoprosthetic Reconstruction of the Proximal Tibia: How Long Do They Last?
title_short Cemented Endoprosthetic Reconstruction of the Proximal Tibia: How Long Do They Last?
title_sort cemented endoprosthetic reconstruction of the proximal tibia: how long do they last?
topic Symposium: Highlights of the ISOLS/MSTS 2009 Meeting
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2947676/
https://www.ncbi.nlm.nih.gov/pubmed/20495967
http://dx.doi.org/10.1007/s11999-010-1390-9
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