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Oncogenic osteomalacia: Problems in diagnosis and long-term management

Oncogenic osteomalacia is a rare association between mesenchymal tumors and hypophosphatemic rickets. It is more of a biochemical entity than a clinical one. The pathophysiology of the tumor is not clear. However, it has been seen that the clinical and biochemical parameters become normal if the les...

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Detalles Bibliográficos
Autores principales: Dhammi, Ish K, Jain, Anil K, Singh, Ajay Pal, Mishra, Puneet, Jain, Saurabh
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2947736/
https://www.ncbi.nlm.nih.gov/pubmed/20924490
http://dx.doi.org/10.4103/0019-5413.69320
Descripción
Sumario:Oncogenic osteomalacia is a rare association between mesenchymal tumors and hypophosphatemic rickets. It is more of a biochemical entity than a clinical one. The pathophysiology of the tumor is not clear. However, it has been seen that the clinical and biochemical parameters become normal if the lesion responsible for producing the osteomalacia is excised. For a clinical diagnosis a high index of suspicion is necessary. We present three such cases where in one the oncogenic osteomalacia reversed while in rest it did not. We present this case report to sensitize about the entity.