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A critical role for the NFkB pathway in multiple myeloma

NFkB transcription factors play a key role in the survival and proliferation of many kinds of B-cell tumors, including multiple myeloma (MM). It was shown that NFkB activation in MM tumors results mainly from extrinsic signaling by APRIL and BAFF ligands that stimulate receptors on normal plasma cel...

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Detalles Bibliográficos
Autores principales: Demchenko, Yulia N., Kuehl, W. Michael
Formato: Texto
Lenguaje:English
Publicado: Impact Journals LLC 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2947827/
https://www.ncbi.nlm.nih.gov/pubmed/20890394