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Brain Mitochondrial Dysfunction in Aging, Neurodegeneration, and Parkinson's Disease
Brain senescence and neurodegeneration occur with a mitochondrial dysfunction characterized by impaired electron transfer and by oxidative damage. Brain mitochondria of old animals show decreased rates of electron transfer in complexes I and IV, decreased membrane potential, increased content of the...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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Frontiers Research Foundation
2010
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2947925/ https://www.ncbi.nlm.nih.gov/pubmed/20890446 http://dx.doi.org/10.3389/fnagi.2010.00034 |