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HIV Promoter Integration Site Primarily Modulates Transcriptional Burst Size Rather Than Frequency

Mammalian gene expression patterns, and their variability across populations of cells, are regulated by factors specific to each gene in concert with its surrounding cellular and genomic environment. Lentiviruses such as HIV integrate their genomes into semi-random genomic locations in the cells the...

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Detalles Bibliográficos
Autores principales: Skupsky, Ron, Burnett, John C., Foley, Jonathan E., Schaffer, David V., Arkin, Adam P.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2947985/
https://www.ncbi.nlm.nih.gov/pubmed/20941390
http://dx.doi.org/10.1371/journal.pcbi.1000952