HapX-Mediated Adaption to Iron Starvation Is Crucial for Virulence of Aspergillus fumigatus

Iron is essential for a wide range of cellular processes. Here we show that the bZIP-type regulator HapX is indispensable for the transcriptional remodeling required for adaption to iron starvation in the opportunistic fungal pathogen Aspergillus fumigatus. HapX represses iron-dependent and mitochon...

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Detalles Bibliográficos
Autores principales: Schrettl, Markus, Beckmann, Nicola, Varga, John, Heinekamp, Thorsten, Jacobsen, Ilse D., Jöchl, Christoph, Moussa, Tarek A., Wang, Shaohua, Gsaller, Fabio, Blatzer, Michael, Werner, Ernst R., Niermann, William C., Brakhage, Axel A., Haas, Hubertus
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2947994/
https://www.ncbi.nlm.nih.gov/pubmed/20941352
http://dx.doi.org/10.1371/journal.ppat.1001124

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