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Malignant Transformation of Non-Neoplastic Barrett's Epithelial Cells through Well-Defined Genetic Manipulations
BACKGROUND: Human Barrett's cancer cell lines have numerous, poorly-characterized genetic abnormalities and, consequently, those lines have limited utility as models for studying the early molecular events in carcinogenesis. Cell lines with well-defined genetic lesions that recapitulate various...
Autores principales: | Zhang, Xi, Yu, Chunhua, Wilson, Kathleen, Zhang, Hui Ying, Melton, Shelby D., Huo, Xiaofang, Wang, David H., Genta, Robert M., Spechler, Stuart J., Souza, Rhonda F. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2948040/ https://www.ncbi.nlm.nih.gov/pubmed/20927195 http://dx.doi.org/10.1371/journal.pone.0013093 |
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