Selectivity Mechanism of the Nuclear Pore Complex Characterized by Single Cargo Tracking

The Nuclear Pore Complex (NPC) mediates all exchange between the cytoplasm and the nucleus. Small molecules can passively diffuse through the NPC, while larger cargos require transport receptors to translocate1. How the NPC facilitates the translocation of transport receptor/cargo complexes remains...

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Detalles Bibliográficos
Autores principales: Lowe, Alan R., Siegel, Jake J., Kalab, Petr, Siu, Merek, Weis, Karsten, Liphardt, Jan T.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2948059/
https://www.ncbi.nlm.nih.gov/pubmed/20811366
http://dx.doi.org/10.1038/nature09285

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