Prevalence of Anticardiolipin Antibodies in Pregnancies with History of Repeated Miscarriages

AIM: This study aimed at evaluating the prevalence of high anticardiolipin antibody and lupus anticoagulant levels in women with histories of at least two miscarriages. METHODS: The presence of high anticardiolipin antibody and lupus anticoagulant levels were evaluated in 52 patients with ages betwe...

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Autores principales: Spegiorin, Ligia Cosentino Junqueira Franco, Galão, Eloísa A, Bagarelli, Lúcia Buchalla, Oliani, Antonio Hélio, de Godoy, José Maria Pereira
Formato: Texto
Lenguaje:English
Publicado: Bentham Open 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2948133/
https://www.ncbi.nlm.nih.gov/pubmed/20890453
http://dx.doi.org/10.2174/1874312901004010028
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author Spegiorin, Ligia Cosentino Junqueira Franco
Galão, Eloísa A
Bagarelli, Lúcia Buchalla
Oliani, Antonio Hélio
de Godoy, José Maria Pereira
author_facet Spegiorin, Ligia Cosentino Junqueira Franco
Galão, Eloísa A
Bagarelli, Lúcia Buchalla
Oliani, Antonio Hélio
de Godoy, José Maria Pereira
author_sort Spegiorin, Ligia Cosentino Junqueira Franco
collection PubMed
description AIM: This study aimed at evaluating the prevalence of high anticardiolipin antibody and lupus anticoagulant levels in women with histories of at least two miscarriages. METHODS: The presence of high anticardiolipin antibody and lupus anticoagulant levels were evaluated in 52 patients with ages between 17 and 41 (mean 26.7 years old) who had histories of repeated miscarriages. RESULTS: High anticardiolipin antibody levels were identified in 55.77% and lupus anticoagulant levels in 2% of the individuals. CONCLUSION: In conclusion, women who suffer from repeated miscarriages present with a high prevalence of anticardiolipin antibodies. Further studies on this issue are crucial as these antibodies are associated with hypercoagulability and thus increased the risk of thromboembolic events.
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spelling pubmed-29481332010-10-01 Prevalence of Anticardiolipin Antibodies in Pregnancies with History of Repeated Miscarriages Spegiorin, Ligia Cosentino Junqueira Franco Galão, Eloísa A Bagarelli, Lúcia Buchalla Oliani, Antonio Hélio de Godoy, José Maria Pereira Open Rheumatol J Article AIM: This study aimed at evaluating the prevalence of high anticardiolipin antibody and lupus anticoagulant levels in women with histories of at least two miscarriages. METHODS: The presence of high anticardiolipin antibody and lupus anticoagulant levels were evaluated in 52 patients with ages between 17 and 41 (mean 26.7 years old) who had histories of repeated miscarriages. RESULTS: High anticardiolipin antibody levels were identified in 55.77% and lupus anticoagulant levels in 2% of the individuals. CONCLUSION: In conclusion, women who suffer from repeated miscarriages present with a high prevalence of anticardiolipin antibodies. Further studies on this issue are crucial as these antibodies are associated with hypercoagulability and thus increased the risk of thromboembolic events. Bentham Open 2010-08-26 /pmc/articles/PMC2948133/ /pubmed/20890453 http://dx.doi.org/10.2174/1874312901004010028 Text en © Spegiorin et al.; Licensee Bentham Open. http://creativecommons.org/licenses/by-nc/3.0/ This is an open access article licensed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
spellingShingle Article
Spegiorin, Ligia Cosentino Junqueira Franco
Galão, Eloísa A
Bagarelli, Lúcia Buchalla
Oliani, Antonio Hélio
de Godoy, José Maria Pereira
Prevalence of Anticardiolipin Antibodies in Pregnancies with History of Repeated Miscarriages
title Prevalence of Anticardiolipin Antibodies in Pregnancies with History of Repeated Miscarriages
title_full Prevalence of Anticardiolipin Antibodies in Pregnancies with History of Repeated Miscarriages
title_fullStr Prevalence of Anticardiolipin Antibodies in Pregnancies with History of Repeated Miscarriages
title_full_unstemmed Prevalence of Anticardiolipin Antibodies in Pregnancies with History of Repeated Miscarriages
title_short Prevalence of Anticardiolipin Antibodies in Pregnancies with History of Repeated Miscarriages
title_sort prevalence of anticardiolipin antibodies in pregnancies with history of repeated miscarriages
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2948133/
https://www.ncbi.nlm.nih.gov/pubmed/20890453
http://dx.doi.org/10.2174/1874312901004010028
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