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A cyclic-RGD-BioShuttle functionalized with TMZ by DAR(inv) “Click Chemistry” targeted to α(v)β(3) integrin for therapy
Clinical experiences often document, that a successful tumor control requires high doses of drug applications. It is widely believed that unavoidable adverse reactions could be minimized by using gene-therapeutic strategies protecting the tumor-surrounding healthy tissue as well as the bone-marrow....
Autores principales: | Braun, Klaus, Wiessler, Manfred, Pipkorn, Rüdiger, Ehemann, Volker, Bäuerle, Tobias, Fleischhacker, Heinz, Müller, Gabriele, Lorenz, Peter, Waldeck, Waldemar |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2948216/ https://www.ncbi.nlm.nih.gov/pubmed/20922134 |
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