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HIV-1 host interactions: integration of large-scale datasets

HIV-1 replication and viral pathogenesis are dependent on numerous host factors. A series of recent papers apply genome-wide and large-scale approaches to map host-virus interactions and to identify host proteins capable of restricting (that is, controlling) the virus. Strategies include genome-wide...

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Detalles Bibliográficos
Autor principal: Telenti, Amalio
Formato: Texto
Lenguaje:English
Publicado: Biology Reports Ltd 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2948256/
https://www.ncbi.nlm.nih.gov/pubmed/20948616
http://dx.doi.org/10.3410/B1-71
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author Telenti, Amalio
author_facet Telenti, Amalio
author_sort Telenti, Amalio
collection PubMed
description HIV-1 replication and viral pathogenesis are dependent on numerous host factors. A series of recent papers apply genome-wide and large-scale approaches to map host-virus interactions and to identify host proteins capable of restricting (that is, controlling) the virus. Strategies include genome-wide association studies, small interfering RNA screens, genome-wide transcriptome profiling, proteome studies, and the assessment of the role of host-encoded microRNAs in infection. The various layers of large-scale data are brought together through meta-analytical procedures.
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spelling pubmed-29482562010-10-14 HIV-1 host interactions: integration of large-scale datasets Telenti, Amalio F1000 Biol Rep Review Article HIV-1 replication and viral pathogenesis are dependent on numerous host factors. A series of recent papers apply genome-wide and large-scale approaches to map host-virus interactions and to identify host proteins capable of restricting (that is, controlling) the virus. Strategies include genome-wide association studies, small interfering RNA screens, genome-wide transcriptome profiling, proteome studies, and the assessment of the role of host-encoded microRNAs in infection. The various layers of large-scale data are brought together through meta-analytical procedures. Biology Reports Ltd 2009-09-28 /pmc/articles/PMC2948256/ /pubmed/20948616 http://dx.doi.org/10.3410/B1-71 Text en © 2009 Biology Reports Ltd http://creativecommons.org/licenses/by-nc/3.0/legalcode This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. You may not use this work for commercial purposes
spellingShingle Review Article
Telenti, Amalio
HIV-1 host interactions: integration of large-scale datasets
title HIV-1 host interactions: integration of large-scale datasets
title_full HIV-1 host interactions: integration of large-scale datasets
title_fullStr HIV-1 host interactions: integration of large-scale datasets
title_full_unstemmed HIV-1 host interactions: integration of large-scale datasets
title_short HIV-1 host interactions: integration of large-scale datasets
title_sort hiv-1 host interactions: integration of large-scale datasets
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2948256/
https://www.ncbi.nlm.nih.gov/pubmed/20948616
http://dx.doi.org/10.3410/B1-71
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