Intracellular trafficking and signaling in development

Tissue patterning during development relies on cell communication by secreted proteins and receptors that engage in complex signaling crosstalk to induce distinct cell behaviors in a context-dependent fashion. Here I summarize recent insights into basic mechanisms that control the distribution and a...

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Detalles Bibliográficos
Autor principal: Constam, Daniel B
Formato: Texto
Lenguaje:English
Publicado: Biology Reports Ltd 2009
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2948274/
https://www.ncbi.nlm.nih.gov/pubmed/20948625
http://dx.doi.org/10.3410/B1-59
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author Constam, Daniel B
author_facet Constam, Daniel B
author_sort Constam, Daniel B
collection PubMed
description Tissue patterning during development relies on cell communication by secreted proteins and receptors that engage in complex signaling crosstalk to induce distinct cell behaviors in a context-dependent fashion. Here I summarize recent insights into basic mechanisms that control the distribution and activities of transforming growth factor beta, Wnt, Hedgehog, and Notch proteins, by regulating trafficking decisions during secretion and endocytosis.
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spelling pubmed-29482742010-10-14 Intracellular trafficking and signaling in development Constam, Daniel B F1000 Biol Rep Review Article Tissue patterning during development relies on cell communication by secreted proteins and receptors that engage in complex signaling crosstalk to induce distinct cell behaviors in a context-dependent fashion. Here I summarize recent insights into basic mechanisms that control the distribution and activities of transforming growth factor beta, Wnt, Hedgehog, and Notch proteins, by regulating trafficking decisions during secretion and endocytosis. Biology Reports Ltd 2009-08-17 /pmc/articles/PMC2948274/ /pubmed/20948625 http://dx.doi.org/10.3410/B1-59 Text en © 2009 Biology Reports Ltd http://creativecommons.org/licenses/by-nc/3.0/legalcode This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. You may not use this work for commercial purposes
spellingShingle Review Article
Constam, Daniel B
Intracellular trafficking and signaling in development
title Intracellular trafficking and signaling in development
title_full Intracellular trafficking and signaling in development
title_fullStr Intracellular trafficking and signaling in development
title_full_unstemmed Intracellular trafficking and signaling in development
title_short Intracellular trafficking and signaling in development
title_sort intracellular trafficking and signaling in development
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2948274/
https://www.ncbi.nlm.nih.gov/pubmed/20948625
http://dx.doi.org/10.3410/B1-59
work_keys_str_mv AT constamdanielb intracellulartraffickingandsignalingindevelopment

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