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Inhibitor of Apoptosis (IAP) proteins as drug targets for the treatment of cancer

Three companies, Genentech, Aegera Therapeutics/Human Genome Sciences, and Novartis, have commenced phase 1 clinical trials of inhibitor of apoptosis (IAP) antagonist ‘Smac mimetic’ compounds for the treatment of cancer. These trials represent the culmination of a line of research that commenced wit...

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Detalles Bibliográficos
Autor principal:	Vaux, David L
Formato:	Texto
Lenguaje:	English
Publicado:	Biology Reports Ltd 2009
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2948278/ https://www.ncbi.nlm.nih.gov/pubmed/20948609 http://dx.doi.org/10.3410/B1-79

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