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A direct measurement of crossing over in human prophase oocytes
The nature of the relationship between crossing over and failed segregation in human oocytes is of obvious interest. A recent paper by Cheng and colleagues provides important insights into the distribution of crossover events (as marked by MLH1 foci) in human oocytes and raises complex questions reg...
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Formato: | Texto |
Lenguaje: | English |
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Biology Reports Ltd
2009
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2948288/ https://www.ncbi.nlm.nih.gov/pubmed/20948604 http://dx.doi.org/10.3410/B1-86 |
Sumario: | The nature of the relationship between crossing over and failed segregation in human oocytes is of obvious interest. A recent paper by Cheng and colleagues provides important insights into the distribution of crossover events (as marked by MLH1 foci) in human oocytes and raises complex questions regarding discrepancies between direct cytological assessment of exchange and measurement of crossing over by linkage analysis. |
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