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A direct measurement of crossing over in human prophase oocytes
The nature of the relationship between crossing over and failed segregation in human oocytes is of obvious interest. A recent paper by Cheng and colleagues provides important insights into the distribution of crossover events (as marked by MLH1 foci) in human oocytes and raises complex questions reg...
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Formato: | Texto |
Lenguaje: | English |
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Biology Reports Ltd
2009
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2948288/ https://www.ncbi.nlm.nih.gov/pubmed/20948604 http://dx.doi.org/10.3410/B1-86 |
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author | Hawley, R Scott |
author_facet | Hawley, R Scott |
author_sort | Hawley, R Scott |
collection | PubMed |
description | The nature of the relationship between crossing over and failed segregation in human oocytes is of obvious interest. A recent paper by Cheng and colleagues provides important insights into the distribution of crossover events (as marked by MLH1 foci) in human oocytes and raises complex questions regarding discrepancies between direct cytological assessment of exchange and measurement of crossing over by linkage analysis. |
format | Text |
id | pubmed-2948288 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2009 |
publisher | Biology Reports Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-29482882010-10-14 A direct measurement of crossing over in human prophase oocytes Hawley, R Scott F1000 Biol Rep Review Article The nature of the relationship between crossing over and failed segregation in human oocytes is of obvious interest. A recent paper by Cheng and colleagues provides important insights into the distribution of crossover events (as marked by MLH1 foci) in human oocytes and raises complex questions regarding discrepancies between direct cytological assessment of exchange and measurement of crossing over by linkage analysis. Biology Reports Ltd 2009-11-16 /pmc/articles/PMC2948288/ /pubmed/20948604 http://dx.doi.org/10.3410/B1-86 Text en © 2009 Biology Reports Ltd http://creativecommons.org/licenses/by-nc/3.0/legalcode This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. You may not use this work for commercial purposes |
spellingShingle | Review Article Hawley, R Scott A direct measurement of crossing over in human prophase oocytes |
title | A direct measurement of crossing over in human prophase oocytes |
title_full | A direct measurement of crossing over in human prophase oocytes |
title_fullStr | A direct measurement of crossing over in human prophase oocytes |
title_full_unstemmed | A direct measurement of crossing over in human prophase oocytes |
title_short | A direct measurement of crossing over in human prophase oocytes |
title_sort | direct measurement of crossing over in human prophase oocytes |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2948288/ https://www.ncbi.nlm.nih.gov/pubmed/20948604 http://dx.doi.org/10.3410/B1-86 |
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