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Anti-insulin growth factor receptor therapy in Ewing sarcoma
The insulin-like growth factor (IGF) signal transduction pathway appears to play a key role in the development and proliferation of the Ewing sarcoma family of tumors. Integration of anti-IGF-1 receptor therapy into the standard treatment for these patients is a novel approach that will likely be in...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Medicine Reports Ltd
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2948310/ https://www.ncbi.nlm.nih.gov/pubmed/20948718 http://dx.doi.org/10.3410/M1-62 |
| _version_ | 1782187443345162240 |
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| author | Isakoff, Michael S Marina, Neyssa |
| author_facet | Isakoff, Michael S Marina, Neyssa |
| author_sort | Isakoff, Michael S |
| collection | PubMed |
| description | The insulin-like growth factor (IGF) signal transduction pathway appears to play a key role in the development and proliferation of the Ewing sarcoma family of tumors. Integration of anti-IGF-1 receptor therapy into the standard treatment for these patients is a novel approach that will likely be incorporated into future treatment to determine whether such agents will improve the outcome for patients with this malignancy. |
| format | Text |
| id | pubmed-2948310 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2009 |
| publisher | Medicine Reports Ltd |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-29483102010-10-14 Anti-insulin growth factor receptor therapy in Ewing sarcoma Isakoff, Michael S Marina, Neyssa F1000 Med Rep Review Article The insulin-like growth factor (IGF) signal transduction pathway appears to play a key role in the development and proliferation of the Ewing sarcoma family of tumors. Integration of anti-IGF-1 receptor therapy into the standard treatment for these patients is a novel approach that will likely be incorporated into future treatment to determine whether such agents will improve the outcome for patients with this malignancy. Medicine Reports Ltd 2009-08-17 /pmc/articles/PMC2948310/ /pubmed/20948718 http://dx.doi.org/10.3410/M1-62 Text en © 2009 Medicine Reports Ltd http://creativecommons.org/licenses/by-nc/3.0/legalcode This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. You may not use this work for commercial purposes |
| spellingShingle | Review Article Isakoff, Michael S Marina, Neyssa Anti-insulin growth factor receptor therapy in Ewing sarcoma |
| title | Anti-insulin growth factor receptor therapy in Ewing sarcoma |
| title_full | Anti-insulin growth factor receptor therapy in Ewing sarcoma |
| title_fullStr | Anti-insulin growth factor receptor therapy in Ewing sarcoma |
| title_full_unstemmed | Anti-insulin growth factor receptor therapy in Ewing sarcoma |
| title_short | Anti-insulin growth factor receptor therapy in Ewing sarcoma |
| title_sort | anti-insulin growth factor receptor therapy in ewing sarcoma |
| topic | Review Article |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2948310/ https://www.ncbi.nlm.nih.gov/pubmed/20948718 http://dx.doi.org/10.3410/M1-62 |
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