Recent advances in mast cell clonality and anaphylaxis

Clonal expansion of mast cells carrying the D816V c-kit mutation results in mastocytosis. Recent studies identified the presence of clonal mast cells carrying this mutation in patients with anaphylaxis without classic diagnostic findings of systemic mastocytosis.

Detalles Bibliográficos
Autor principal: Akin, Cem
Formato: Texto
Lenguaje:English
Publicado: Medicine Reports 2009
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2948323/
https://www.ncbi.nlm.nih.gov/pubmed/20948680
http://dx.doi.org/10.3410/M1-97
Descripción
Sumario:Clonal expansion of mast cells carrying the D816V c-kit mutation results in mastocytosis. Recent studies identified the presence of clonal mast cells carrying this mutation in patients with anaphylaxis without classic diagnostic findings of systemic mastocytosis.

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