An update on pathobiologic roles of anti-glycan antibodies in Guillain-Barré syndrome

Anti-glycan antibodies directed against gangliosides are now considered the major immune effectors that induce damage to intact nerve fibers in some variants of the monophasic neuropathic disorders that comprise Guillain-Barré syndrome. Recent experimental studies elucidating the complexity of anti-...

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Detalles Bibliográficos
Autores principales: Sheikh, Kazim A, Zhang, Gang
Formato: Texto
Lenguaje:English
Publicado: Faculty of 1000 Ltd 2010
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2948347/
https://www.ncbi.nlm.nih.gov/pubmed/20948812
http://dx.doi.org/10.3410/B2-21
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author Sheikh, Kazim A
Zhang, Gang
author_facet Sheikh, Kazim A
Zhang, Gang
author_sort Sheikh, Kazim A
collection PubMed
description Anti-glycan antibodies directed against gangliosides are now considered the major immune effectors that induce damage to intact nerve fibers in some variants of the monophasic neuropathic disorders that comprise Guillain-Barré syndrome. Recent experimental studies elucidating the complexity of anti-glycan antibody-mediated pathobiologic effects on intact and injured nerves undergoing repair are discussed.
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spelling pubmed-29483472010-10-14 An update on pathobiologic roles of anti-glycan antibodies in Guillain-Barré syndrome Sheikh, Kazim A Zhang, Gang F1000 Biol Rep Review Article Anti-glycan antibodies directed against gangliosides are now considered the major immune effectors that induce damage to intact nerve fibers in some variants of the monophasic neuropathic disorders that comprise Guillain-Barré syndrome. Recent experimental studies elucidating the complexity of anti-glycan antibody-mediated pathobiologic effects on intact and injured nerves undergoing repair are discussed. Faculty of 1000 Ltd 2010-03-25 /pmc/articles/PMC2948347/ /pubmed/20948812 http://dx.doi.org/10.3410/B2-21 Text en © 2010 Faculty of 1000 Ltd http://creativecommons.org/licenses/by-nc/3.0/legalcode This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. You may not use this work for commercial purposes
spellingShingle Review Article
Sheikh, Kazim A
Zhang, Gang
An update on pathobiologic roles of anti-glycan antibodies in Guillain-Barré syndrome
title An update on pathobiologic roles of anti-glycan antibodies in Guillain-Barré syndrome
title_full An update on pathobiologic roles of anti-glycan antibodies in Guillain-Barré syndrome
title_fullStr An update on pathobiologic roles of anti-glycan antibodies in Guillain-Barré syndrome
title_full_unstemmed An update on pathobiologic roles of anti-glycan antibodies in Guillain-Barré syndrome
title_short An update on pathobiologic roles of anti-glycan antibodies in Guillain-Barré syndrome
title_sort update on pathobiologic roles of anti-glycan antibodies in guillain-barré syndrome
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2948347/
https://www.ncbi.nlm.nih.gov/pubmed/20948812
http://dx.doi.org/10.3410/B2-21
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