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Why is Pseudomonas aeruginosa a pathogen?
Despite the expression of a myriad of virulence factors, healthy individuals are generally able to resist infections with Pseudomonas aeruginosa. Polymorphonuclear leukocyte-dependent killing is the major mechanism responsible for resistance; dysregulation of host defense mechanisms in addition to e...
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| Formato: | Texto |
| Lenguaje: | English |
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Faculty of 1000 Ltd
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2948353/ https://www.ncbi.nlm.nih.gov/pubmed/20948804 http://dx.doi.org/10.3410/B2-29 |
| Sumario: | Despite the expression of a myriad of virulence factors, healthy individuals are generally able to resist infections with Pseudomonas aeruginosa. Polymorphonuclear leukocyte-dependent killing is the major mechanism responsible for resistance; dysregulation of host defense mechanisms in addition to expression of specific bacterial factors can result in life-threatening infections with this bacterium. |
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