Why is Pseudomonas aeruginosa a pathogen?

Despite the expression of a myriad of virulence factors, healthy individuals are generally able to resist infections with Pseudomonas aeruginosa. Polymorphonuclear leukocyte-dependent killing is the major mechanism responsible for resistance; dysregulation of host defense mechanisms in addition to e...

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Detalles Bibliográficos
Autor principal: Goldberg, Joanna B
Formato: Texto
Lenguaje:English
Publicado: Faculty of 1000 Ltd 2010
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2948353/
https://www.ncbi.nlm.nih.gov/pubmed/20948804
http://dx.doi.org/10.3410/B2-29
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author Goldberg, Joanna B
author_facet Goldberg, Joanna B
author_sort Goldberg, Joanna B
collection PubMed
description Despite the expression of a myriad of virulence factors, healthy individuals are generally able to resist infections with Pseudomonas aeruginosa. Polymorphonuclear leukocyte-dependent killing is the major mechanism responsible for resistance; dysregulation of host defense mechanisms in addition to expression of specific bacterial factors can result in life-threatening infections with this bacterium.
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spelling pubmed-29483532010-10-14 Why is Pseudomonas aeruginosa a pathogen? Goldberg, Joanna B F1000 Biol Rep Review Article Despite the expression of a myriad of virulence factors, healthy individuals are generally able to resist infections with Pseudomonas aeruginosa. Polymorphonuclear leukocyte-dependent killing is the major mechanism responsible for resistance; dysregulation of host defense mechanisms in addition to expression of specific bacterial factors can result in life-threatening infections with this bacterium. Faculty of 1000 Ltd 2010-04-27 /pmc/articles/PMC2948353/ /pubmed/20948804 http://dx.doi.org/10.3410/B2-29 Text en © 2010 Faculty of 1000 Ltd http://creativecommons.org/licenses/by-nc/3.0/legalcode This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. You may not use this work for commercial purposes
spellingShingle Review Article
Goldberg, Joanna B
Why is Pseudomonas aeruginosa a pathogen?
title Why is Pseudomonas aeruginosa a pathogen?
title_full Why is Pseudomonas aeruginosa a pathogen?
title_fullStr Why is Pseudomonas aeruginosa a pathogen?
title_full_unstemmed Why is Pseudomonas aeruginosa a pathogen?
title_short Why is Pseudomonas aeruginosa a pathogen?
title_sort why is pseudomonas aeruginosa a pathogen?
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2948353/
https://www.ncbi.nlm.nih.gov/pubmed/20948804
http://dx.doi.org/10.3410/B2-29
work_keys_str_mv AT goldbergjoannab whyispseudomonasaeruginosaapathogen

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