Advances in understanding the interaction between the gut microbiota and adaptive mucosal immune responses

Commensal gut bacteria are necessary for the complete development of mucosal innate and adaptive immunity and thus may influence intestinal and systemic immune disorders. Recent work has advanced our understanding of this association by identification of a single taxon of the murine microbiota which...

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Detalles Bibliográficos
Autores principales: Neish, Andrew S, Denning, Timothy L
Formato: Texto
Lenguaje:English
Publicado: Faculty of 1000 Ltd 2010
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2948354/
https://www.ncbi.nlm.nih.gov/pubmed/20948806
http://dx.doi.org/10.3410/B2-27
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author Neish, Andrew S
Denning, Timothy L
author_facet Neish, Andrew S
Denning, Timothy L
author_sort Neish, Andrew S
collection PubMed
description Commensal gut bacteria are necessary for the complete development of mucosal innate and adaptive immunity and thus may influence intestinal and systemic immune disorders. Recent work has advanced our understanding of this association by identification of a single taxon of the murine microbiota which can stimulate T-cell development and differentiation. It is hoped that further characterization of the mechanisms involved will enable targeted manipulation of the microbiota-immune system relationship.
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spelling pubmed-29483542010-10-14 Advances in understanding the interaction between the gut microbiota and adaptive mucosal immune responses Neish, Andrew S Denning, Timothy L F1000 Biol Rep Review Article Commensal gut bacteria are necessary for the complete development of mucosal innate and adaptive immunity and thus may influence intestinal and systemic immune disorders. Recent work has advanced our understanding of this association by identification of a single taxon of the murine microbiota which can stimulate T-cell development and differentiation. It is hoped that further characterization of the mechanisms involved will enable targeted manipulation of the microbiota-immune system relationship. Faculty of 1000 Ltd 2010-04-12 /pmc/articles/PMC2948354/ /pubmed/20948806 http://dx.doi.org/10.3410/B2-27 Text en © 2010 Faculty of 1000 Ltd http://creativecommons.org/licenses/by-nc/3.0/legalcode This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. You may not use this work for commercial purposes
spellingShingle Review Article
Neish, Andrew S
Denning, Timothy L
Advances in understanding the interaction between the gut microbiota and adaptive mucosal immune responses
title Advances in understanding the interaction between the gut microbiota and adaptive mucosal immune responses
title_full Advances in understanding the interaction between the gut microbiota and adaptive mucosal immune responses
title_fullStr Advances in understanding the interaction between the gut microbiota and adaptive mucosal immune responses
title_full_unstemmed Advances in understanding the interaction between the gut microbiota and adaptive mucosal immune responses
title_short Advances in understanding the interaction between the gut microbiota and adaptive mucosal immune responses
title_sort advances in understanding the interaction between the gut microbiota and adaptive mucosal immune responses
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2948354/
https://www.ncbi.nlm.nih.gov/pubmed/20948806
http://dx.doi.org/10.3410/B2-27
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AT denningtimothyl advancesinunderstandingtheinteractionbetweenthegutmicrobiotaandadaptivemucosalimmuneresponses

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