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Mapping chromatin conformation
Chromatin conformation capture (3C) and related techniques have become well-established methods to examine which distal DNA sequences are spatially located close to a locus of interest. Hi-C is a new addition to the growing set of 3C-based techniques that has extended the approach to a genome-wide a...
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Formato: | Texto |
Lenguaje: | English |
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Faculty of 1000 Ltd
2010
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2948366/ https://www.ncbi.nlm.nih.gov/pubmed/20948815 http://dx.doi.org/10.3410/B2-18 |
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author | Shaw, Peter J |
author_facet | Shaw, Peter J |
author_sort | Shaw, Peter J |
collection | PubMed |
description | Chromatin conformation capture (3C) and related techniques have become well-established methods to examine which distal DNA sequences are spatially located close to a locus of interest. Hi-C is a new addition to the growing set of 3C-based techniques that has extended the approach to a genome-wide analysis of nuclear chromatin using high-throughput DNA sequencing to generate global interaction maps for the entire genome. |
format | Text |
id | pubmed-2948366 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2010 |
publisher | Faculty of 1000 Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-29483662010-10-14 Mapping chromatin conformation Shaw, Peter J F1000 Biol Rep Review Article Chromatin conformation capture (3C) and related techniques have become well-established methods to examine which distal DNA sequences are spatially located close to a locus of interest. Hi-C is a new addition to the growing set of 3C-based techniques that has extended the approach to a genome-wide analysis of nuclear chromatin using high-throughput DNA sequencing to generate global interaction maps for the entire genome. Faculty of 1000 Ltd 2010-03-15 /pmc/articles/PMC2948366/ /pubmed/20948815 http://dx.doi.org/10.3410/B2-18 Text en © 2010 Faculty of 1000 Ltd http://creativecommons.org/licenses/by-nc/3.0/legalcode This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. You may not use this work for commercial purposes |
spellingShingle | Review Article Shaw, Peter J Mapping chromatin conformation |
title | Mapping chromatin conformation |
title_full | Mapping chromatin conformation |
title_fullStr | Mapping chromatin conformation |
title_full_unstemmed | Mapping chromatin conformation |
title_short | Mapping chromatin conformation |
title_sort | mapping chromatin conformation |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2948366/ https://www.ncbi.nlm.nih.gov/pubmed/20948815 http://dx.doi.org/10.3410/B2-18 |
work_keys_str_mv | AT shawpeterj mappingchromatinconformation |