Cargando…
Rapid cleavage of RNA by RNase E in the absence of 5′ monophosphate stimulation
The best characterized pathway for the initiation of mRNA degradation in Escherichia coli involves the removal of the 5′-terminal pyrophosphate to generate a monophosphate group that stimulates endonucleolytic cleavage by RNase E. We show here however, using well-characterized oligonucleotide substr...
Autores principales: | Kime, Louise, Jourdan, Stefanie S, Stead, Jonathan A, Hidalgo-Sastre, Ana, McDowall, Kenneth J |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2010
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2948425/ https://www.ncbi.nlm.nih.gov/pubmed/19889093 http://dx.doi.org/10.1111/j.1365-2958.2009.06935.x |
Ejemplares similares
-
Direct entry by RNase E is a major pathway for the degradation and processing of RNA in Escherichia coli
por: Clarke, Justin E., et al.
Publicado: (2014) -
The recognition of structured elements by a conserved groove distant from domains associated with catalysis is an essential determinant of RNase E
por: Clarke, Justin E, et al.
Publicado: (2023) -
Adjacent single-stranded regions mediate processing of tRNA precursors by RNase E direct entry
por: Kime, Louise, et al.
Publicado: (2014) -
The First Small-Molecule Inhibitors of Members of the Ribonuclease E Family
por: Kime, Louise, et al.
Publicado: (2015) -
Erratum: The First Small-Molecule Inhibitors of Members of the Ribonuclease E Family
por: Kime, Louise, et al.
Publicado: (2015)