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Ganglioside metabolism in a transgenic mouse model of Alzheimer's disease: expression of Chol-1α antigens in the brain
The accumulation of Aβ (amyloid β-protein) is one of the major pathological hallmarks in AD (Alzheimer's disease). Gangliosides, sialic acid-containing glycosphingolipids enriched in the nervous system and frequently used as biomarkers associated with the biochemical pathology of neurological d...
Autores principales: | Ariga, Toshio, Yanagisawa, Makoto, Wakade, Chandramohan, Ando, Susumu, Buccafusco, Jerry J, McDonald, Michael P, Yu, Robert K |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Society for Neurochemistry
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2948441/ https://www.ncbi.nlm.nih.gov/pubmed/20930939 http://dx.doi.org/10.1042/AN20100021 |
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