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RNAi Experiments in D. melanogaster: Solutions to the Overlooked Problem of Off-Targets Shared by Independent dsRNAs

BACKGROUND: RNAi technology is widely used to downregulate specific gene products. Investigating the phenotype induced by downregulation of gene products provides essential information about the function of the specific gene of interest. When RNAi is applied in Drosophila melanogaster or Caenorhabdi...

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Detalles Bibliográficos
Autores principales:	Seinen, Erwin, Burgerhof, Johannes G. M., Jansen, Ritsert C., Sibon, Ody C. M.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2948504/ https://www.ncbi.nlm.nih.gov/pubmed/20957038 http://dx.doi.org/10.1371/journal.pone.0013119

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