PHOX2B-Mediated Regulation of ALK Expression: In Vitro Identification of a Functional Relationship between Two Genes Involved in Neuroblastoma

BACKGROUND: Neuroblastoma (NB) is a severe pediatric tumor originating from neural crest derivatives and accounting for 15% of childhood cancer mortality. The heterogeneous and complex genetic etiology has been confirmed with the identification of mutations in two genes, encoding for the receptor ty...

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Detalles Bibliográficos
Autores principales: Bachetti, Tiziana, Di Paolo, Daniela, Di Lascio, Simona, Mirisola, Valentina, Brignole, Chiara, Bellotti, Marta, Caffa, Irene, Ferraris, Chiara, Fiore, Michele, Fornasari, Diego, Chiarle, Roberto, Borghini, Silvia, Pfeffer, Ulrich, Ponzoni, Mirco, Ceccherini, Isabella, Perri, Patrizia
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2948505/
https://www.ncbi.nlm.nih.gov/pubmed/20957039
http://dx.doi.org/10.1371/journal.pone.0013108

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