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Failure of Effector Function of Human CD8(+) T Cells in NOD/SCID/JAK3(−/−) Immunodeficient Mice Transplanted with Human CD34(+) Hematopoietic Stem Cells

Humanized mice, which are generated by transplanting human CD34(+) hematopoietic stem cells into immunodeficient mice, are expected to be useful for the research on human immune responses. It is reported that antigen-specific T cell responses occur in immunodeficient mice transplanted with both huma...

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Detalles Bibliográficos
Autores principales:	Sato, Yoshinori, Takata, Hiroshi, Kobayashi, Naoki, Nagata, Sayaka, Nakagata, Naomi, Ueno, Takamasa, Takiguchi, Masafumi
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2948507/ https://www.ncbi.nlm.nih.gov/pubmed/20957041 http://dx.doi.org/10.1371/journal.pone.0013109

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