The Anti-Inflammatory Drug Leflunomide Is an Agonist of the Aryl Hydrocarbon Receptor

BACKGROUND: The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that mediates the toxicity and biological activity of dioxins and related chemicals. The AhR influences a variety of processes involved in cellular growth and differentiation, and recent studies have suggested...

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Detalles Bibliográficos
Autores principales: O'Donnell, Edmond F., Saili, Katerine S., Koch, Daniel C., Kopparapu, Prasad R., Farrer, David, Bisson, William H., Mathew, Lijoy K., Sengupta, Sumitra, Kerkvliet, Nancy I., Tanguay, Robert L., Kolluri, Siva Kumar
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2948512/
https://www.ncbi.nlm.nih.gov/pubmed/20957046
http://dx.doi.org/10.1371/journal.pone.0013128

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2948512/
https://www.ncbi.nlm.nih.gov/pubmed/20957046
http://dx.doi.org/10.1371/journal.pone.0013128

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