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Thermosensitive Pluronic(®) hydrogel: prolonged injectable formulation for drug abuse
OBJECTIVE: The main objective of this study was to investigate thermosensitive Pluronic(®) F-127 (PF-127) hydrogel for the modified release of a potent alcohol and opioid antagonist, naltrexone (NTX) hydrochloride, in a subcutaneous injectable dosage form. METHODS: The NTX hydrogels were prepared by...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2948935/ https://www.ncbi.nlm.nih.gov/pubmed/20957216 |