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Role of structural MRI in Alzheimer's disease

Atrophy measured on structural magnetic resonance imaging (sMRI) is a powerful biomarker of the stage and intensity of the neurodegenerative aspect of Alzheimer's disease (AD) pathology. In this review, we will discuss the role of sMRI as an AD biomarker by summarizing (a) the most commonly use...

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Detalles Bibliográficos
Autores principales: Vemuri, Prashanthi, Jack, Clifford R
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2949589/
https://www.ncbi.nlm.nih.gov/pubmed/20807454
http://dx.doi.org/10.1186/alzrt47
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author Vemuri, Prashanthi
Jack, Clifford R
author_facet Vemuri, Prashanthi
Jack, Clifford R
author_sort Vemuri, Prashanthi
collection PubMed
description Atrophy measured on structural magnetic resonance imaging (sMRI) is a powerful biomarker of the stage and intensity of the neurodegenerative aspect of Alzheimer's disease (AD) pathology. In this review, we will discuss the role of sMRI as an AD biomarker by summarizing (a) the most commonly used methods to extract information from sMRI images, (b) the different roles in which sMRI can be used as an AD biomarker, and (c) comparisons of sMRI with other major AD biomarkers.
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spelling pubmed-29495892011-08-31 Role of structural MRI in Alzheimer's disease Vemuri, Prashanthi Jack, Clifford R Alzheimers Res Ther Review Atrophy measured on structural magnetic resonance imaging (sMRI) is a powerful biomarker of the stage and intensity of the neurodegenerative aspect of Alzheimer's disease (AD) pathology. In this review, we will discuss the role of sMRI as an AD biomarker by summarizing (a) the most commonly used methods to extract information from sMRI images, (b) the different roles in which sMRI can be used as an AD biomarker, and (c) comparisons of sMRI with other major AD biomarkers. BioMed Central 2010-08-31 /pmc/articles/PMC2949589/ /pubmed/20807454 http://dx.doi.org/10.1186/alzrt47 Text en Copyright ©2010 BioMed Central Ltd
spellingShingle Review
Vemuri, Prashanthi
Jack, Clifford R
Role of structural MRI in Alzheimer's disease
title Role of structural MRI in Alzheimer's disease
title_full Role of structural MRI in Alzheimer's disease
title_fullStr Role of structural MRI in Alzheimer's disease
title_full_unstemmed Role of structural MRI in Alzheimer's disease
title_short Role of structural MRI in Alzheimer's disease
title_sort role of structural mri in alzheimer's disease
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2949589/
https://www.ncbi.nlm.nih.gov/pubmed/20807454
http://dx.doi.org/10.1186/alzrt47
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AT jackcliffordr roleofstructuralmriinalzheimersdisease