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Tumor senescence and radioresistant tumor-initiating cells (TICs): let sleeping dogs lie!
Preclinical data from cell lines and experimental tumors support the concept that breast cancer-derived tumor-initiating cells (TICs) are relatively resistant to ionizing radiation and chemotherapy. This could be a major determinant of tumor recurrence following treatment. Increased clonogenic survi...
Autores principales: | Zafarana, Gaetano, Bristow, Robert G |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2949629/ https://www.ncbi.nlm.nih.gov/pubmed/20619004 http://dx.doi.org/10.1186/bcr2597 |
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