HER3 and downstream pathways are involved in colonization of brain metastases from breast cancer

INTRODUCTION: Metastases to the brain from breast cancer have a high mortality, and basal-like breast cancers have a propensity for brain metastases. However, the mechanisms that allow cells to colonize the brain are unclear. METHODS: We used morphology, immunohistochemistry, gene expression and som...

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Detalles Bibliográficos
Autores principales: Da Silva, Leonard, Simpson, Peter T, Smart, Chanel E, Cocciardi, Sibylle, Waddell, Nic, Lane, Annette, Morrison, Brian J, Vargas, Ana Cristina, Healey, Sue, Beesley, Jonathan, Pakkiri, Pria, Parry, Suzanne, Kurniawan, Nyoman, Reid, Lynne, Keith, Patricia, Faria, Paulo, Pereira, Emilio, Skalova, Alena, Bilous, Michael, Balleine, Rosemary L, Do, Hongdo, Dobrovic, Alexander, Fox, Stephen, Franco, Marcello, Reynolds, Brent, Khanna, Kum Kum, Cummings, Margaret, Chenevix-Trench, Georgia, Lakhani, Sunil R
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2949633/
https://www.ncbi.nlm.nih.gov/pubmed/20604919
http://dx.doi.org/10.1186/bcr2603

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