Anti-tumor effects of retinoids combined with trastuzumab or tamoxifen in breast cancer cells: induction of apoptosis by retinoid/trastuzumab combinations

INTRODUCTION: HER2 and estrogen receptor (ER) are important in breast cancer and are therapeutic targets of trastuzumab (Herceptin) and tamoxifen, respectively. Retinoids inhibit breast cancer growth, and modulate signaling by HER2 and ER. We hypothesized that treatment with retinoids and simultaneo...

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Detalles Bibliográficos
Autores principales: Koay, Debbie C, Zerillo, Cynthia, Narayan, Murli, Harris, Lyndsay N, DiGiovanna, Michael P
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2949655/
https://www.ncbi.nlm.nih.gov/pubmed/20696059
http://dx.doi.org/10.1186/bcr2625

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2949655/
https://www.ncbi.nlm.nih.gov/pubmed/20696059
http://dx.doi.org/10.1186/bcr2625

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