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A prophylactic vaccine for breast cancer?

Cancer vaccines are the Holy Grail for patients and clinicians alike. The possibility that we can be vaccinated against common cancers is very appealing and the socioeconomic consequences are significant. A recent paper from Vincent Tuohy's group, published in the journal Nature Medicine, sugge...

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Detalles Bibliográficos
Autores principales: Watson, Christine J, Gusterson, Barry A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2949658/
https://www.ncbi.nlm.nih.gov/pubmed/20828424
http://dx.doi.org/10.1186/bcr2628
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author Watson, Christine J
Gusterson, Barry A
author_facet Watson, Christine J
Gusterson, Barry A
author_sort Watson, Christine J
collection PubMed
description Cancer vaccines are the Holy Grail for patients and clinicians alike. The possibility that we can be vaccinated against common cancers is very appealing and the socioeconomic consequences are significant. A recent paper from Vincent Tuohy's group, published in the journal Nature Medicine, suggests a new approach for the development of a prophylactic vaccine for breast cancer. Their strategy was to induce mammary gland failure in mice by immunisation with an antibody specific to a milk protein that resulted in autoimmunity during lactation. This also showed some efficacy as a therapeutic vaccine. Can we look forward to the elimination of breast cancer?
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spelling pubmed-29496582011-02-28 A prophylactic vaccine for breast cancer? Watson, Christine J Gusterson, Barry A Breast Cancer Res Viewpoint Cancer vaccines are the Holy Grail for patients and clinicians alike. The possibility that we can be vaccinated against common cancers is very appealing and the socioeconomic consequences are significant. A recent paper from Vincent Tuohy's group, published in the journal Nature Medicine, suggests a new approach for the development of a prophylactic vaccine for breast cancer. Their strategy was to induce mammary gland failure in mice by immunisation with an antibody specific to a milk protein that resulted in autoimmunity during lactation. This also showed some efficacy as a therapeutic vaccine. Can we look forward to the elimination of breast cancer? BioMed Central 2010 2010-08-31 /pmc/articles/PMC2949658/ /pubmed/20828424 http://dx.doi.org/10.1186/bcr2628 Text en Copyright ©2010 BioMed Central Ltd
spellingShingle Viewpoint
Watson, Christine J
Gusterson, Barry A
A prophylactic vaccine for breast cancer?
title A prophylactic vaccine for breast cancer?
title_full A prophylactic vaccine for breast cancer?
title_fullStr A prophylactic vaccine for breast cancer?
title_full_unstemmed A prophylactic vaccine for breast cancer?
title_short A prophylactic vaccine for breast cancer?
title_sort prophylactic vaccine for breast cancer?
topic Viewpoint
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2949658/
https://www.ncbi.nlm.nih.gov/pubmed/20828424
http://dx.doi.org/10.1186/bcr2628
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