Differential expression of DKK-1 binding receptors on stromal cells and myeloma cells results in their distinct response to secreted DKK-1 in myeloma

BACKGROUND: The canonical Wnt signaling is concurrently important for osteoblast differentiation and myeloma cell proliferation. Its activation in myeloma cells and its inhibition in osteoblasts and their progenitors have been identified in the previous studies. Osteoblast progenitors and myeloma ce...

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Detalles Bibliográficos
Autores principales: Dun, Xiaoyi, Jiang, Hua, Zou, Jianfeng, Shi, Jun, Zhou, Lili, Zhu, Rong, Hou, Jian
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2949801/
https://www.ncbi.nlm.nih.gov/pubmed/20846389
http://dx.doi.org/10.1186/1476-4598-9-247

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