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Co-expression of nuclear and cytoplasmic HMGB1 is inversely associated with infiltration of CD45RO+ T cells and prognosis in patients with stage IIIB colon cancer

BACKGROUND: The intratumoral infiltration of T cells, especially memory T cells, is associated with a favorable prognosis in early colorectal cancers. However, the mechanism underlying this process remains elusive. This study examined whether high-mobility group box 1 (HMGB1), a damage-associated mo...

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Detalles Bibliográficos
Autores principales: Peng, Rui-Qing, Wu, Xiao-Jun, Ding, Ya, Li, Chun-Yan, Yu, Xing-Juan, Zhang, Xing, Pan, Zhi-Zhong, Wan, De-Sen, Zheng, Li-Ming, Zeng, Yi-Xin, Zhang, Xiao-Shi
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2949807/
https://www.ncbi.nlm.nih.gov/pubmed/20846416
http://dx.doi.org/10.1186/1471-2407-10-496