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High-risk HPV E5-induced cell fusion: a critical initiating event in the early stage of HPV-associated cervical cancer

BACKGROUND: Cervical cancer is strongly associated with high-risk human papillomavirus (HPV) and viral oncoproteins E5, E6 and E7 can transform cells by various mechanisms. It is proposed that oncogenic virus-induced cell fusion may contribute to oncogenesis if p53 or apoptosis is perturbed simultan...

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Detalles Bibliográficos
Autores principales: Gao, Peng, Zheng, Jie
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2949840/
https://www.ncbi.nlm.nih.gov/pubmed/20846406
http://dx.doi.org/10.1186/1743-422X-7-238