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Increased expression of RXRα in dementia: an early harbinger for the cholesterol dyshomeostasis?
BACKGROUND: Cholesterol content of cerebral membranes is tightly regulated by elaborate mechanisms that balance the level of cholesterol synthesis, uptake and efflux. Among the conventional regulatory elements, a recent research focus has been nuclear receptors, a superfamily of ligand-activated tra...
Autores principales: | Akram, Afia, Schmeidler, James, Katsel, Pavel, Hof, Patrick R, Haroutunian, Vahram |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2949865/ https://www.ncbi.nlm.nih.gov/pubmed/20843353 http://dx.doi.org/10.1186/1750-1326-5-36 |
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