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PRDM9 sticks its zinc fingers into recombination hotspots and between species
Meiotic recombination events typically cluster within narrow regions of the genome termed hotspots. A series of recent papers reveals that PRDM9, a C2H2-type zinc-finger protein with histone H3 lysine 4 methyltransferase activity, plays a major role in the specification of hotspots. The zinc fingers...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Faculty of 1000 Ltd
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2950028/ https://www.ncbi.nlm.nih.gov/pubmed/20948797 http://dx.doi.org/10.3410/B2-37 |