Seeing with the mind’s eye: top-down, bottom-up, and conscious awareness

With the advent of functional brain imaging techniques and recent developments in the analysis of cortical connectivity, the focus of mental imagery studies has shifted from a semi-modular approach to an integrated cortical network perspective. Functional magnetic resonance imaging studies of visual imagery of faces and objects show that activation of content-specific representations stored in the ventral visual stream is top-down-modulated by parietal and frontal regions. Recent findings in patients with conscious awareness disorders reveal that mental imagery can be used to map patterns of residual cognitive function in their brain and to provide diagnostic and prognostic indicators.